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The Comprehensive Cancer Center at St. Jude comprises several cross-disciplinary, multi-departmental programs oriented to specific diseases (Hematological Malignancies and Neurobiology & Brain Tumor), conceptual themes (Signal Transduction and Molecular Oncology) or novel therapeutic approaches (Developmental Biology and Solid Tumor). The Cancer Center also includes a new Cancer Prevention & Control Program, which builds on the institution’s commitment to long-term follow-up of patients in the After Completion of Therapy Clinic.