In order for our site to display correctly you will need a newer version of your web browser.
The following browsers support numerous web standards including CSS,XHTML, and the DOM (a universal means of controlling the behavior of web pages):
- Netscape v7 or higher (all platforms), Mozilla FireFox (Windows), Camino (Mac OS X), Galeon (Linux GNOME Desktop) or other browser stemming from the Mozilla.org project.
- Opera v7 or higher (Windows, Linux)
- Apple's Safari (Mac OS X)
- Konqueror (Linux KDE Desktop)
- Microsoft Internet Explorer v6 or higher (Windows) or v5 or higher (Macintosh)
Please note that this is not intended be an exhaustive list of browsers that support web standards, nor a test of browser compliance, nor a side-by-side comparison of various manufacturers’ browsers.
Finding Cures. Saving Children.
2005 News Release Archive
A new strategy that turns small populations of immune system cells into armies that track down and kill neuroblastoma throughout the body could save the lives of many children each year.
A new strategy for treating childhood AML based on the individual patient's risk of failure, and guided by the results of a sensitive technique for identifying leukemic cells, yielded one-year survival rates of almost 90 percent, according to St. Jude.
A protein called TRAF3, with a previously unknown job in immune cells, is a key part of a mechanism that triggers release of anti-virus molecules called type I interferons as part of the body's rapid response against these invaders, according to St. Jude.
Adults who abuse cocaine might increase their risk of developing Parkinson's disease (PD), and pregnant women who abuse cocaine could increase the risk of their children developing PD later in life.
A protein called Scythe determines which cells live and which die during the growth and development of the mammalian embryo.
The disruption of a molecular bridge that holds together the molecule p53 tends to destabilize this protein, allowing it to form potentially disease-causing aggregates, or "clumps," according to a study by investigators at St. Jude.
A biochemical mechanism that cells use to cope with hypoxia (lack of oxygen) actually cooperates with a less well-known mechanism that helps increase the expression of those hypoxia-sensitive genes, according to investigators at St. Jude.
Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators at St. Jude.
The ability of the brain to transmit and process information requires a lifelong commitment to maintaining the integrity of synapses-the special connections that permit the passage of nerve impulses from one nerve cell to another.
The Ink4c and Ptch1 genes collaborate to suppress the development of medulloblastoma, the most common pediatric brain tumor, according to investigators at St. Jude, Rockefeller University, Johns Hopkins University and the University of Newcastle (UK).
Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital.
Studies using laboratory models of retinoblastoma show that the combination of topotecan and carboplatin are superior to the current multi-drug treatment.
How mitochondria are recruited during times of stress to choreograph apoptosis - the cell's dance of death - is a story that fails to tell which particular set of steps the cells use most often, according to investigators at St. Jude and La Jolla.
Investigators at St. Jude have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress.
Pediatric cancer patients as young as 10 years old who are aware that their disease is incurable have the ability to participate meaningfully in discussions of their own end-of-life care with family members and the health care team
FOXO1a caused death of tumor cells in laboratory study by triggering expression of caspase-3, which blocks cell division and causes cells to undergo apoptosis.
Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.
Almost immediately after Hurricane Katrina swept through the Gulf Coast area, wreaking death and untold destruction, employees of St. Jude leapt into action.
Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America.
The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs.
Pediatric patients from the devastated Gulf Coast area have been airlifted to St. Jude Children's Research Hospital today where they will receive vital cancer treatment disrupted by Hurricane Katrina in the New Orleans and Gulf Coast regions.
St. Jude has responded to the needs of non-St. Jude pediatric cancer patients in the storm damaged areas of New Orleans by assisting in referring those patients to St. Jude affiliates in Louisiana.
St. Jude will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia and eliminate need for nightly injections with drug that reduces iron overload.
Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude.
Irradiation therapy for the brain cancer medulloblastoma is more likely to impair IQ and reading skills of younger children than older children even if the dose of radiation is reduced, according to the results of the largest study of its kind.
A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.
Inserting biopsy needles through the skin appears to be a safe and reliable alternative to surgery for obtaining diagnostic samples of a suspected solid tumor in children, according to results of a study by investigators at St. Jude.
Cells control mitosis (cell division) by assembling a biochemical switch to block it or by disassembling the switch to trigger it...
As a cell moves forward, physical stress on its skeleton triggers molecular fingers and arms to grasp each other in reinforcing links that stabilize the skeleton, according to images produced by investigators at St. Jude Children's Research Hospital.
Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).
Treating babies who have sickle cell anemia with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude.
Tom Curran, Ph.D., chair of the department of Developmental Neurobiology and co-leader of the Neurobiology and Brain Tumor Program at St. Jude Children's Research Hospital, has been elected to the Fellowship of the Royal Society.
The emergence of cancer as a major cause of death among children in developing regions of the world is not being adequately addressed by national or international health organizations and charities, according to investigators at St. Jude.
Drugs that block the enzyme Odc prevent the onset of cancers that would otherwise be triggered by a family of cancer-causing genes called Myc, according to investigators at St. Jude Children's Research Hospital.
Scientists at St. Jude Children's Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system.
Accelerated approval of the drug clofarabine to treat relapsed or refractory pediatric acute lymphoblastic leukemia (ALL) shows the importance of offering children rapid access to new treatments through clinical trials, said investigators at St. Jude.
The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL).
Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells.
The genes TEL2 and MYC cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma.
Some children with a rare brain tumor that is considered almost universally fatal can be saved if they receive radiation therapy followed by tandem (given one after the other) cycles of high-dose chemotherapy.
The outcome of chemotherapy treatment for acute lymphoblastic leukemia (ALL) depends not only on the acquired genetic make-up of the leukemic cells, but on genes that children inherit from their parents.
Finding that Mcl-1 blocks cell suicide in hematopoietic stem cells also suggests that interfering with this protein might improve leukemia treatment.
A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body.
Experts in the fields of retinoblastoma research and treatment will gather to update colleagues on the latest developments in these fields during a two-day symposium April 28-29 at St. Jude.
Cure4Kids.org has achieved a milestone reaching Cote d'Ivoire, the 100th country to join the program.
Measuring the quantity of a certain type of immune cell DNA in the blood could help physicians predict whether a bone marrow stem cell transplant will successfully restore a population of infection-fighting cells called T lymphocytes in a child.
