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Different sub-classes of a type of white blood cell involved in autoimmune diseases such as multiple sclerosis (MS) arise independently within the immune system, according to a finding from St. Jude scientists that provides new insight into how autoimmunity is controlled.
Immunologists have made great strides in enlisting the body’s own immune cells to fight cancers and infections.
St. Jude researchers have discovered an intriguing insight into how T cells, the immune system’s master regulatory cells, wage war on the body’s own tissues in such autoimmune disorders as multiple sclerosis, type 1 diabetes and rheumatoid arthritis.
St. Jude researchers demonstrated a way to short-circuit uncontrolled autoimmune responses, thereby preventing or curing a serious immune system disease called autoimmune encephalomyelitis (inflammation of the brain and spinal cord).