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oThe pre-stem cell transplant evaluation is conducted to assess the patient’s clinical condition and eligibility for protocol enrollment before transplantation. Typically, the pre-evaluation requires re-staging studies that may include bone marrow studies, diagnostic imaging, and organ function studies to be performed within 30 days of enrollment on a research protocol. In addition, blood work to assess blood counts, liver and kidney function, electrolyte concentrations, infectious disease markers and HLA-typing are typically performed. Specific studies of heart, lung, kidney and liver function are also included. These tests are necessary to determine that the patient is able to undergo the stem cell transplant process.
At the time of the pre-evaluation, patients are seen by specialists in ophthalmology, clinical nutrition, social work and physical therapy. All patients must have a double or triple lumen central line placed before the stem cell transplant is undertaken. The central line is needed to allow efficient administration of chemotherapy, medications and blood product transfusions the patient requires.