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There is some evidence that children with sickle cell disease have altered protein metabolism and increased protein needs. Children with sickle cell disease are often shorter and thinner than their healthy peers.
Patients should be encouraged to follow a nutritious, well balanced diet to prevent malnutrition. Small, frequent feeding of calorie and protein-dense foods is encouraged to increase intake. Generally, the diet should provide at least 120 percent to 150 percent of the Recommended Dietary Allowances for calories and protein depending on the child's age, height, weight, medical status, and nutrition goals.