Rachel C. Brennan, MD
Assistant Member, St. Jude Faculty
Departments
Oncology
Divisions
Solid Tumor
Contact Information
Rachel Brennan, MD
Solid Tumor
MS 260, Room C6066
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: rachel.brennan@stjude.org
Phone: (901) 595-2573
FAX: (901) 521-9005
Education
BA – Carroll College, Helena, Montana
MD – Johns Hopkins University School of Medicine, Baltimore, Maryland
Internship/Residency (Pediatrics) - Johns Hopkins Hospital
Fellowship (Pediatric Hematology/Oncology) - St. Jude Children’s Research Hospital
Research Interests
- Retinoblastoma: therapy and late effects
- Translating preclinical research into clinical trials (Lab Liaison)
- Phase I clinical trials
- Renal tumors
- Minimizing early and late complications of chemotherapy
Selected Publications
Brennan RC, Wilson MW, Kaste S, Helton KJ, McCarville MB. US and MRI of pediatric ocular masses with histopathological correlation. Pediatr Radiol March 31, 2012.
McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, Bradley C, Krafcik F, Rodriguez-Galindo C, Wilson M, Xiong S, Lozano G, Sage J, Fu L, Louhibi L, Trimarchi J, Pani A, Smeyne R, Johnson D, Dyer MA. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell 20(2):260-75, 2011.
Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, Shurtleff S, Mullighan C, Pounds S, Mukatira S, Gupta P, Neale G, Zhao D, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Naeve C, Dyson NJ, Mardis ER, Bahrami A, Ellison D, Wilson RK, Downing JR, Dyer MA. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 481(7381):329-34, 2012.
Brennan R, Federico S, Bradley C, Zhang J, Flores-Otero J, Wilson M, Stewart C, Zhu F, Guy K, Dyer MA. Targeting the p53 Pathway in Retinoblastoma with Subconjunctival Nutlin-3a. Cancer Res Apr 22, 2011 (Epub ahead of print).
Teitz T, Stanke J, Federico S, Bradley C, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang Z, Hillenbrand C, Rehg JE, Frase S, Calabrese C, Finkelstein D, Dyer MA, Lahti JM. Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment. PLoS ONE Apr 29;6(4):e19133, 2011.
Brennan R, Helton K, Pei D, Cheng C, Inaba H, Metzger M, Howard S, Rubnitz J, Ribeiro R, Sandlund J, Jeha S, Pui C-H, Bhojwani D. Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol Feb 22, 2011. [Epub ahead of print]
Federico S, Brennan R, Dyer MA. Childhood Cancer and Developmental Biology: A Crucial Partnership. Curr Top Dev Biol 94:1-13, 2011.
Brennan R, Federico S, Dyer MA. The war on cancer: have we won the battle but lost the war? Oncotarget 1:77-83, 2010.
Brennan R. Oncology (Chapter 22). In: Rau, R; Custer, J; Lee CK; The Harriet Lane Handbook. 18th ed. Philadelphia: Elsevier Mosby. 603-614, 2008.
Last updated: April 2012