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    Kanneganti: News Releases & Feature Stories

    Protein identified that serves as a “brake” on inflammation

    Results of the St. Jude Children’s Research Hospital-led study provide a target for developing novel therapies to tame the inflammation that drives autoinflammatory diseases (Thirumala-Devi Kanneganti, PhD)

    Experiments reveal key components of the body’s machinery for battling deadly tularemia

    St. Jude Children’s Research Hospital scientists have discovered major “switches” that activate the immune system to kill the bacterium, potentially leading to protective drugs and vaccines. (Thirumala-Devi Kanneganti, PhD)

    Basic question yields possible strategy for combating major tropical disease

    Researchers like to ask basic questions about how the world and the things in it work. Answers to those questions can advance science and protect health.

    Possible strategy identified to combat major parasitic tropical disease

    St. Jude Children’s Research Hospital scientists report results that suggest neutralizing a single protein may aid fight against a parasitic tropical disease that annually sickens more than 1.3 million people worldwide. (Thirumala-Devi Kanneganti, PhD)

    St. Jude Children’s Research Hospital scientist honored for contributions to immunology

    Thirumala-Devi Kanneganti, Ph.D., of St. Jude Children’s Research Hospital, is recognized by the American Association of Immunologists for outstanding research contributions to the field of immunology. (Thirumala-Devi Kanneganti, PhD)

    Diet affects mix of intestinal bacteria and the risk of inflammatory bone disease

    St. Jude Children’s Research Hospital study finds diet may influence susceptibility to autoinflammatory disease in at-risk individuals by favoring intestinal bacteria that fuel or dampen inflammation. (Thirumala-Devi Kanneganti, PhD)

    Understanding mutation leads to promising new treatment for autoinflammatory diseases

    St. Jude Children’s Research Hospital study yields clues for designing next-generation drugs to treat autoinflammatory diseases. (Dr. Kanneganti)

    Innate immune system protein provides a new target in war against bacterial infections

    Studies led by St. Jude Children’s Research Hospital show that a protein working on the frontlines of the immune response dampens inflammation and might offer a completely new approach to fighting bacterial infections. (Dr. Thirumala-Devi Kanneganti)

    Busted! Foiling the inside job

    Imagine realizing that a trusted security guard has burglarized your house. A similar discovery in the lab may help researchers identify novel treatments for multiple sclerosis.

    New research details the machinery of immune protection against inflammatory disease like colitis

    Scientists report a protein made by a gene already associated with a handful of human inflammatory immune diseases plays a pivotal role in protecting the intestinal tract from colitis.

    Taming dangerous lung inflammation in influenza

    One of the most threatening complications of influenza stems not from the virus itself, but from the overreaction of the immune system. This overreaction can cause persistent lung inflammation that lasts long after the virus has been quelled.