Non-Therapeutic Protocol

BRAIN2: The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease-2

Type of Protocol/Clinical Study

Associated Hematology Studies : Sickle cell disease


Central nervous system complications including stroke, silent infarcts (death of tissue due to a lack of blood flow) and neurocognitive difficulties (difficulty with thinking and learning) are some of the most overwhelming consequences of sickle cell disease (SCD). As a result, young children with SCD may have academic problems. Most studies involving neurocognitive testing of children with SCD have focused on school-aged children; very few have examined preschool-age children. Because thinking and learning difficulties appear to begin before a child with SCD is 5 years old, this study will focus on 3-year olds. The participants will be given the Brigance Preschool Screen-II, one of the most often used tests to study learning development. The duration of the study will be for 3 years.



Inclusion Criteria

Exclusion Criteria

Principal Investigator

Winfred Wang, MD

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