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If the brain housed an exclusive condominium, the facility would likely be in the market for a new security guard. A recent study led by St. Jude Children’s Research Hospital scientists found that a cell surface molecule the brain relies on to act like a security guard—turning away bacteria and other threats—is easily duped.
New research suggests a family of widely used cholesterol-lowering drugs might help protect individuals from serious illness following bacterial infection, including the pneumococcal infections that pose a deadly threat to those with sickle cell disease.
A team led by St. Jude investigators has identified the cell surface receptor that bacteria and other infectious agents must dupe to launch their assault on the brain, a finding that raises hope for a new generation of meningitis vaccines.
The wait is over for scientists at St. Jude who envisioned the day when technology would transform the way they analyze DNA samples. Using new technology that churns out massive amounts of data, investigators now have a comprehensive view of genomes to increase their understanding of cancers and infectious diseases.
The last thing most high school and college students want to do in the summer is more school work. But instead of non-stop texting, lounging by the pool or playing video games, some of the nation’s brightest students spend each summer with some of the world’s hardest working researchers in labs at St. Jude Children’s Research Hospital.
In a new study, St. Jude researchers have gained insight into how pneumococcus, the primary cause of pneumonia, uses a particular piece of stolen genetic material to render it more virulent.
St. Jude investigators discover how pneumonia bacteria "hijack" immune system protein to escape bloodstream, invade heart muscle.
Respiratory infections are the No. 1 killer of children around the world. St. Jude researchers are determined to change that statistic.
Pneumonia bacteria invade the body by hijacking proteins that let the germs enter one side of blood vessel cells and travel through them to reach the brain on the other side, according to St. Jude investigators.
Scientists at St. Jude have discovered that the structure of a protein on the surface of pneumonia bacteria helps these germs invade the human bloodstream, which may lead to a more effective pneumonia vaccine.
Scientists at St. Jude Children's Research Hospital announced today the development of a vaccine against H5N1, a new lethal influenza virus that triggered the World Health Organization (WHO) to declare a pandemic alert in February 2003.