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    Baker: News Releases & Feature Stories

    For brain tumor patients, age matters

    Scientists at St. Jude Children’s Research Hospital have more evidence that age matters when it comes to the devastating brain tumors called high-grade gliomas (HGGs).

    Gene sequencing project discovers mutations tied to deadly brain tumors in young children

    St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients. (Suzanne Baker, PhD, and Jinghui Zhang, PhD)

    Revealing the Secrets of the Genome

    Pediatric Cancer Genome Project scientists begin to uncover treasures.

    Cancer sequencing initiative discovers mutations tied to aggressive childhood brain tumors

    St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project provides first evidence linking cancer to mutations in genes involved in DNA organization. (Dr. Suzanne Baker)

    Writing the Next Chapter

    For many years, St. Jude researchers have been investigating the connection between genetics and pediatric cancer. Those approaches continue to have dramatic implications for clinical care.

    Key regulatory genes often amplified in aggressive childhood tumor of the brainstem

    Study led by St. Jude Children’s Research Hospital scientists points to possible new treatment targets for diffuse intrinsic pontine gliomas; may tip the scales in the current debate about tumor biopsies.

    Key mutations act cooperatively to fuel aggressive brain tumor

    St. Jude Children’s Research Hospital investigators use a novel model system to show how specific mutations can induce glioma formation in multiple regions of the brain and to begin studying patient response to a new generation of targeted therapies.

    Turning the tide

    Clinicians and researchers chart a course to find cures for high-grade gliomas.

    Push to understand basis of childhood brain tumors leads to a new treatment target

    The most comprehensive analysis yet of the genetic imbalances at the heart of childhood brain tumors known as high-grade gliomas (HGGs) identified a cancer gene that is unusually active in some tumors and is now the focus of a St. Jude Children’s Research Hospital clinical trial.

    New drug prevents abnormal brain cell growth in lab mice

    Investigators at St. Jude Children's Research Hospital used an experimental anti-cancer drug to prevent or reverse abnormal brain cell growth that is caused by lack of the anti-cancer gene Pten.