Mark E. Hatley, MD, PhD
Assistant Member, St. Jude Faculty
Departments
Oncology
Divisions
Solid Tumor
Contact Information
Mark Hatley, MD, PhD
Solid Tumor
MS 310, Room D5024F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: mark.hatley@stjude.org
FAX: (901) 595-3966
Education
BS – University of Central Oklahoma, Edmond, Oklahoma
MD, PhD – University of Texas Southwestern Medical Center at Dallas, Medical Scientist Training Program, Dallas, Texas
Research Interests
- Cellular and molecular origins of embryonal rhabdomyosarcoma
- MicroRNAs in pediatric sarcomas
- Mouse models of pediatric sarcomas
- Development of novel therapies for pediatric sarcomas
Selected Publications
Hatley ME, Tang W, Garcia MR, Finkelstein D, Millay DP, Liu N, Graff J, Galindo RL, Olson EN. A mouse model of rhabdomyosarcoma originating from the adipocyte lineage. Cancer Cell 16:536-46, 2012. PMCID: PMC3479681
Hatley ME, Patrick DM, Garcia MR, Ricardson JA, Bassel-Duby R, van Rooij, Olson EN. Modulation of K-ras-dependent lung tumorigenesis by microRNA-21. Cancer Cell 18:282-93, 2010. PMCID: PMC2971666.
Hatley ME, Lockless SW, Gibson SK, Gilman AG, Ranganathan R. Allosteric determinants of guanine nucleotide binding proteins. Proceedings of the National Academy of Science 100:14445-50, 2003.
Hatley ME, Gilman AG, Sunahara RK. Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases. Methods in Enzymology 345:127-40, 2002.
Hatley ME, Benton BK, Xu J, Manfredi JP, Gilman AG, Sunahara RK. Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase. Journal Biological Chemistry 275(49):38626-32, 2000.
O’Hair RAJ, Freitas MA, Schmidt JAR, Hatley ME, Williams TD. Gas-phase methylation fo 2-hydroxypyridine/2-pyridone system by the dimethylchloronium ion. European Mass Spectrometry 1:457-463,1995.
Last update: February 2013