REN534: Treatment for Patients with Bilateral, Multicentric, or Bilaterally- Predisposed Unilateral Wilms Tumor


Solid Tumor : Wilms tumor


Wilms tumor is a type of cancer that occurs in the cells of the kidney. Children with Wilms tumor in both of their kidneys (bilateral) account for 5-7% of all patients with Wilms tumor. Certain patients, with syndromes associated with Wilms tumor development, may have an increased risk for bilateral tumors. The diagnosis of Wilms tumor is based on the types of cells seen in the tumor. Wilms tumor is best treated when it is found early, before it has spread to other areas of the body. The most common way to treat bilateral Wilms tumor is to give two or three common anti-cancer drugs (chemotherapy with vincristine, dactinomycin, and sometimes doxorubicin) to shrink the tumors and then to do surgery to remove the tumor tissue. In some cases, an entire kidney and part of the other kidney are removed. Sometimes radiation therapy (treatment with high energy X-rays) is also done.



For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children's Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).


Rachel Brennan, MD
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105 USA
Voice: 1-888-226-4343 or 901-595-4055
Fax: 901-595-4011

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The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.