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    Persons: News Releases & Feature Stories

     
    09/04/2009
    Scientists advance a two-gene approach to curing beta-thalassemia

    A St. Jude team successfully introduced two new genes into blood-producing bone marrow stem cells in an effort to ease beta-thalassemia in mice and reduce treatment side effects.

     
     
    01/08/2009
    Gene therapy corrects sickle cell disease in laboratory study

    Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude have alleviated sickle cell disease pathology. In their studies, the researchers found that the treated mice showed essentially no difference from normal mice.

     
     
    11/05/2004
    Technique for genetically modifying blood stem cells brings cure for blood diseases closer

    The condition of mice with a genetic blood disease called beta-thalassemia improved significantly following treatment of their blood forming cells with a gene that enabled them to produce the type of hemoglobin normally found only in the fetus.

     
     
    05/01/2003
    St. Jude researchers reverse blood disease using genetically modified stem cells

    Researchers at St. Jude Children's Research Hospital have overcome two major technical obstacles that currently limit the success of gene therapy for human red blood cell diseases such as beta-thalassemia and sickle cell disease.