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(St. Jude Reference #)
|Description||Our researchers have derived peptides from the PB1-F2 protein of the influenza A virus that can be used to treat or prevent gram positive bacterial infection. These peptides have exhibited activity against a variety of medicinally important bacteria including Streptococcus pneumonia, Staphylococcus aureus and Streptococcus pyogenes. These peptides are expected to be effective against antibiotic resistant bacterial strains and do not cause inflammation.|
|Keywords||Influenza, virulence, PB1-F2|
|Granted Patents or Published Applications||U.S. provisional application pending.|
|Related Scientific References||Alvmova, I.V. et al.,”Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82”, J. Virol. 85(23): 12324-12333 (Dec. 2011)|
|Licensing Opportunities||We are currently seeking licensing opportunities for further development and testing of these peptides.|
Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.
Last update: July 2012