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Research
| Technology Name (St. Jude Reference #) |
Anti-bacterial Peptides (SJ-12-0002) |
| Description | Our researchers have derived peptides from the PB1-F2 protein of the influenza A virus that can be used to treat or prevent gram positive bacterial infection. These peptides have exhibited activity against a variety of medicinally important bacteria including Streptococcus pneumonia, Staphylococcus aureus and Streptococcus pyogenes. These peptides are expected to be effective against antibiotic resistant bacterial strains and do not cause inflammation. |
| Keywords | Influenza, virulence, PB1-F2 |
| Granted Patents or Published Applications | U.S. provisional application pending. |
| Related Scientific References | Alvmova, I.V. et al.,”Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82”, J. Virol. 85(23): 12324-12333 (Dec. 2011) |
| Licensing Opportunities | We are currently seeking licensing opportunities for further development and testing of these peptides. |
Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.
Last update: July 2012
