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    Stewart: News Releases & Feature Stories

     
    07/10/2007
    Low doses of drug help kids avoid genetic test

    St. Jude investigators have shown that when the cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to perform costly genetic testing that would delay treatment.

     
     
    01/23/2007
    Scientists gain new insight into drug pump in brain

    St. Jude researchers have found evidence in a mouse model that simultaneous therapy with a drug that regulates movement of topotecan from the bloodstream can reduce its concentration in the cerebrospinal fluid (CSF).

     
     
    05/03/2006
    Simplifying therapy for neuroblastoma

    The best dose of a chemotherapy drug for one child is not necessarily the best dose for another. St. Jude scientists are simplifying individualized therapy for children with cancer.

     
     
    09/12/2005
    Fewer blood samples needed to check drug level

    A team of researchers at St. Jude has figured out how to minimize the number of times children receiving the cancer drug topotecan must have blood samples drawn when performing pharmacokinetic studies, while ensuring accurate results.

     
     
    07/18/2005
    Fine-tuning cancer drug concentrations in neuroblastoma

    Monitoring and fine tuning the levels of the cancer drug topotecan in children with neuroblastoma holds promise for maximizing the drug's effectiveness while reducing its toxicity.