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Leukemias / Lymphomas : Acute myeloid leukemia
At this time approximately 50 percent of children affected by acute myeloid leukemia (AML) are cured. Most of these patients with AML get into remission (cancer cells are wiped out) after one to three courses of induction therapy (initial intensive course of chemotherapy that is designed to wipe out cancer cells), but almost half of them relapse (cancer comes back). Also, despite improvements in supportive care, treatment-related issues and severe illnesses are still a problem. Therefore, the overall goal of our program is to develop new treatments that will overcome drug resistance, decrease relapse rates, and decrease the short-and long-term harmful effects of treatment. This study will evaluate a new form of therapy that includes NK cells and chemotherapy. NK cells are special cells in our immune system that specifically target cancer cells and cells that are infected by viruses. Studies in animals showed that NK cells may help donor cells to grow may reduce the chance of a condition called graft versus host disease (GVHD), and may reduce the chance of relapse.
For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children's Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).
Jeffrey E. Rubnitz, MD, PhD
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105 USA
Voice: 1-866-2ST-JUDE (1-866-278-5833)
Referring or consulting physicians only: email@example.com
For all other inquiries about St. Jude Children's Research Hospital studies: firstname.lastname@example.org
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.