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Finding Cures. Saving Children.
Najat C. Daw, MD
Associate Member, St. Jude Faculty
Departments
Oncology
Divisions
Solid Tumor
Contact Information
Najat Daw, MD
Oncology
MS260, Room C6008
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Phone: (901) 595-2573
FAX: (901) 521-9005
Education
BS - American University of Beirut
MD - American University of Beirut
Research Interests
-
Bone sarcomas
-
Drug development
Selected Publications
Ness KK, Rao BN, Daw NC. More than physical function: HRQOL among children and adolescents with lower extremity bone sarcoma. Pediatr Blood Cancer 2009 (in press).
Wright KD, Green DM, Daw NC. Late effects of treatment for Wilms tumor. Pediatr Hematol Oncol 2009 (in press).
Furman WL, Navid F, Daw NC, McCarville MB, McGregor LM, Spunt SL, Rodriguez-Galindo C, Panetta JC, Crews KR, Wu J, Gajjar AJ, Houghton PJ, Santana VM, Stewart CF. A tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors. J Clin Oncol 2009 (in press).
Hinds PS, Gattuso JS, Billups CA, West NK, Wu J, Rivera C, Quintana J, Villarroel M, Daw NC. Aggressive treatment of nonmetastatic osteosarcoma improves health-related quality of life in children and adolescents. Eur J Cancer [Epub ahead of print] 2009 May 16, 2009.
Klosky JL, Randolph-Frye ME, Navid F, Gamble HL, Spunt SL, Metzger ML, Daw NC, Morris EB, Hudson MM. Sperm cryopreservation practices among adolescent cancer patients at risk for infertility. Pediatr Hematol Oncol 26(4):252-60, 2009
Hoffer FA, Daw NC, Xiong X, Anghelescu D, Krasin M, Yan X, Davidoff AM, Furman WL, Rodriguez-Galindo C, Spunt SL. A phase 1/pilot study of radiofrequency ablation for the treatment of recurrent pediatric solid tumors. Cancer 115(6):1328-37, 2009; [Epub ahead of print] 2009 Jan 29.
Daw NC, Gregornik D, Rodman J, Marina N, Wu J, Kun LE, Jenkins JJ, McPherson V, Wilimas J, Jones DP. Renal function after ifosfamide, carboplatin, and etoposide (ICE) chemotherapy, nephrectomy, and radiotherapy in children with Wilms tumour. Eur J Cancer 45(1):99-106, 2009. [Epub ahead of print] 2008 Nov 6. NIHMS88715
Hinds PS, Billups C, Cao X, Gattuso JS, Burghen E, West N, Rubnitz JE, Daw NC. Health-related quality of life in adolescents at the time of diagnosis with osteosarcoma or acute myeloid leukemia. Eur J Oncol Nurs [Epub ahead of print] 2008 Oct 14.
Freeman SS, Allen SW, Ganti R, Wu J, Ma J, Su X, Neale G, Dome JS, Daw NC, Khoury JD. Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors. Cancer 113(6):1453-61, 2008.
Navid F, Willert JR, McCarville MB, Furman W, Watkins A, Roberts W, Daw NC. Combination of gemcitabine and docetaxel in treatment of children and young adults with refractory bone sarcoma. Cancer 113 (2):419-425, 2008. [Epub ahead of print] 2008 May 16.
Absalon MJ, McCarville MB, Liu T, Santana VM, Daw NC, Navid F. Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma. Pediatr Blood Cancer 50(6):1147-53, 2008.
Rivera GK, Quintana J, Villarroel M, Santana VM, Rodriguez-Galindo C, Neel MN, Velez G, Ribeiro RC, Daw NC. Transfer of complex frontline anticancer therapy to a developing country: The St. Jude osteosarcoma experience in Chile. Pediatr Blood & Cancer 2007 Dec 17; [Epub ahead of print].
Inaba H, Khan RB, Laningham FH, Crews KR, Pui C-H, Daw NC. Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer. Ann Oncol 19(1):178-84, 2008; Epub 2007 Oct 17, 2008.
Lee N, Smolarz AJ, Olson S, David O, Reiser J, Kutner R, Daw NC, Prockop DJ, Horwitz EM, Gregory CA. A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. Br J Cancer 97(11):1552-9, 2007.
Jimeno A, Daw NC, Amador ML, Cusatis G, Kulesza P, Krailo M, Ingle AM, Blaney SM, Adamson P, Hidalgo M. Analysis of biologic surrogate markers from a Children’s Oncology Group Phase I trial of gefitinib in pediatric patients with solid tumors. Pediatr Blood & Cancer 49(3):352-7, 2007.
Metzger ML, Stewart CF, Freeman BB III, Billups CA, Hoffer FA, Wu J, Coppes MJ, Grant R, Chintagumpala M, Mullen EA, Alvarado C, Daw NC, Dome JS. Topotecan is active against Wilms’ tumor: Results of a multi-institutional Phase II study. J Clin Oncol 25(21):3130-6, 2007.
Rodríguez-Galindo C, Liu T, Krasin MJ, Wu J, Billups CA, Daw NC, Spunt SL, Rao BN, Santana VM, Navid F. Analysis of prognostic factors in Ewing sarcoma family of tumors: Review of St. Jude Children’s Research Hospital studies. Cancer 110(2):375-384, 2007.
Weiss A, Khoury JD, Hoffer FA, Wu J, Billups CA, Heck RK, Quintana J, Poe D, Rao BN, Daw NC. Telangiectatic osteosarcoma: The St. Jude Children’s Research Hospital’s experience. Cancer 109(8):1627-1637, 2007.
McCarville MB, Barton EH, Cameron JR, Xiong X, Daw NC, Kaste SC, Wu S, Glass JO, Reddick WE. The cause and clinical significance of central tumor photopenia on thallium scintigraphy of pediatric osteosarcoma of the extremity. Am J Roentgenol 188:572-578, 2007.
Freeman BB, III, Daw NC, Geyer JR, Furman WL, Stewart CF. Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patients. Cancer Invest 24(3):310-317, 2006.
Daw NC, Jenkins JJ, McCarville MB, Rao BN, Neel MN. Polymethylmethacrylate lung embolus after limb-salvage surgery of the distal femur. Clin Orthopaed Rel Res 448:252-256, 2006.
McCarville MB, Lederman H, Santana VM, Daw NC, Shochat SJ, Li C-S, Kaufman RA. Distinguishing benign from malignant pulmonary nodules with helical chest CT in children with malignant solid tumors. Radiology 239(2):514-520, 2006.
Turner PK, Iacono LC, Panetta JC, Santana VM, Daw NC, Gajjar A, Stewart CF. Development and validation of limited sampling models for topotecan lactone pharmacokinetic studies in children. Cancer Chemother Pharmacol 57(4):475-482, 2006.
Furman WL, Crews KR, Billups C, Wu J, Gajjar AJ, Daw NC, Patrick CC, Rodriguez-Galindo C, Stewart CF, Dome JS, Panetta JC, Houghton PJ, Santana VM. Cefixime allows greater dose escalation of oral irinotecan: A phase I study in pediatric patients with refractory solid tumors. J Clin Oncol 24(4):563-570, 2006.
Hartford CM, Wodowski KS, Rao BN, Khoury JD, Neel MD, Daw NC. Osteosarcoma among children aged 5 years or younger: The St. Jude Children’s Research Hospital experience. J Pediatr Hematol Oncol 28:43-47, 2006.
Daw NC, Billups CA, Rodriguez-Galindo C, McCarville MB, Rao BN, Cain AM, Jenkins JJ, Neel MD, Meyer WH. Metastatic osteosarcoma: Results of two consecutive therapeutic trials at St. Jude Children's Research Hospital. Cancer 106:403-412, 2006.
Rodriguez-Galindo C, Crews KR, Stewart CF, Furman W, Panetta JC, Daw NC, Cain A, Tan M, Houghton PJ, Santana VM. Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors. Cancer Chemother Pharmacol 57(1):15-24, 2006.
Kaste SC, Fuller CE, Saharia A, Rao BN, Daw NC. Pediatric surface osteosarcoma: Clinical, pathologic, and radiologic features. Pediatr Blood & Cancer 47(2):152-162 [Epub ahead of print, Aug 25, 2005], 2006.
Last update: May 2009
