Translational Imaging Research Division



Translational Imaging Research is a division of the Department of Radiological Sciences.  It was established in 2004. Prior to 2004, Translational Imaging Research was a section of the Diagnostic Imaging division.

Current Divisional Objectives

The new Division of Translational Imaging Research (DTIR) is building upon a solid base of independent research programs working toward a common goal of understanding and thus minimizing the impact of cancer and its treatment on children. These programs currently focus on:

  • using MR technology to characterize the relationship between cancer treatment, neurostructural organization and integrity, and neurocognitive performance in children
  • using functional MR technology to define the relations between acquired deficits in neurocognitive performance and therapy-induced brain injury in children
  • using innovative adaptive image processing procedures for automatic quantitative analysis of brain structures in children with brain tumors

These research programs are pursued through a combination of basic and clinical research. 

Basic research has focused on the development of innovative algorithms and methods to quantitatively characterize the structure and function of the developing brains of children treated for cancer.

Clinical research within DTIR has translated this basic research into hypotheses driven objectives incorporated into treatment protocols in the Hematological Malignancies, Neurobiology & Brain Tumor, and Cancer Prevention & Control Programs.

Analysis Tools

The computational facilities in the Division of Translational Imaging Research are configured on a UNIX distributed processing structure centered on common NFS shared file systems.

We have three servers, one file server and two computational servers. The file server is a Silicon Graphics Inc. (SGI®) Origin® 350 with three terabytes of file space. The computational servers are an SGI® Altix® 350 and an SGI® Origin® 300. We installed the Altix® in December of 2004 and it is our most powerful server. Four Itanium®2, 1.6 GHz processors drive the server.

The software applications used to analyze MRI data include Matlab®, Statistical Parameter Mapping (SPM), FLTK, C, C++, Free Surfer, FSL and AFNI.

Future Activity

In the spring of 2007, the Division of Translational Imaging Research will move to the new Integrated Patient Care and Research Building (IPCRB). This building is currently under construction. Read more about the Integrated Patient Care and Research Building.

 

 


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