After high dose methotrexate for leukemiaAfter receiving high dose methotrexate for leukemia, it is important that your child stays well-hydrated. She will also be given other medicines by IV for at least 2 days after receiving high dose methotrexate.
After high dose methotrexate for solid tumorsAfter receiving high dose methotrexate for solid tumors, it is important that your child stays well-hydrated. For this reason, your child will receive IV fluids by a portable pump for at least 3 days after receiving high dose methotrexate.
Chemotherapy by mouth at homeOral chemotherapy (chemo) is any cancer-fighting drug that the patient will take by mouth. It can be in the form of a tablet, capsule, or liquid.
Children and teens taking antidepressantsAntidepressants are drugs used, most often, to treat depression. Depression is a complex illness that involves sad and hopeless feelings that do not go away. Read this handout to learn more about depression and the benefits and risks of taking antidepressants.
Cytochrome P450 2D6 (CYP2D6) and medicinesWhen you take a medicine (drug), your body has to have a way to handle the medicine. One way is for
enzymes to metabolize (break down) the medicine. A family of enzymes called cytochrome P450s have the ability to break down certain medicines.
Oral syringes vs. IV syringesMany times when we hear the word syringe, we think of a syringe that is used to inject medicine into the body. But, a different type of syringe is used to give medicines by mouth (oral). These syringes are a great way to measure oral liquid medicine, so each dose is accurate.
PharmacokineticsPharmacokinetics is an important section of the Pharmaceutical Sciences department at St. Jude. The staff in Pharmacokinetics works hard to find out: how much, how often, how long certain medicines should be given to your child to achieve the best results.
SLCO1B1 and medicinesWhen you take a medicine (drug), your body has to have a way to handle the medicine. One way is for carriers to transport medicines. A transporter called solute carrier organic anion transporter family member 1B1 (SLCO1B1) helps the body get rid of certain medicines after they are no longer needed.
Thiopurine methyltransferase (TPMT) and medicinesWhen you take a medicine (drug), your body has to have a way to handle the medicine. One way is for
enzymes to metabolize (break down) the medicine. An enzyme called thiopurine methyltransferase (TPMT) has the ability to break down a class of medicines called thiopurines.
Treatment risks if pregnantSometimes medical treatments can delay the start of menstrual periods. However, a girl can still become pregnant even if she has never had a period or has stopped having periods because of medical treatments.
Research
