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An international research collaborative led by St. Jude Children’s Research Hospital reports that the rapid action of (+)-SJ733 will likely slow malaria drug resistance; human safety trials of the compound are planned. (R. Kiplin Guy, PhD)
For many years, St. Jude researchers have been investigating the connection between genetics and pediatric cancer. Those approaches continue to have dramatic implications for clinical care.
A small molecule developed at St. Jude Children’s Research Hospital advances progress toward more tailored drugs in research that also offers insight into the biology of thyroid hormone.
Research led by St. Jude Children’s Research Hospital investigators used a pioneering approach to drug development and identified dozens of potential new treatments of ependymoma, a rare tumor of the brain and spinal cord.
Sometimes two wrongs do, in fact, make a right
An international team led by St. Jude Children’s Research Hospital investigators today released data detailing the effectiveness of nearly 310,000 chemicals against a malaria parasite that remains one of the world’s leading killers of young children.
Whenever family and friends are invited to your home, chances are the evening will end with everyone lingering in the kitchen. Perhaps someone has a warm pot of coffee to share, a story or a hearty laugh. Whatever the attraction, the heart of the home beats strongest when everyone joins together. At St. Jude Children’s Research Hospital, the Chemical Biology and Therapeutics (CBT) department serves a similar role.
St. Jude data collection now occurs in minutes instead of days, thanks to shared resources at Argonne National Laboratory. And in the past couple of months, St. Jude access to the facility has skyrocketed.
A St. Jude investigator was a key player in a national team of researchers that brought scientists a step closer to finding a cure for brain-degeneration diseases caused by abnormal proteins called prions.
The appointment of three nationally renowned investigators to major faculty positions will significantly bolster research aimed at increasing survival rates of children with cancer while reducing treatment toxicity.