Related Topics

    Grosveld: News Releases & Feature Stories

    St. Jude researchers identify key genetic trigger of AML

    A gene called N-Myc leads a double life in certain white blood cells when it is overexpressed, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a study done by St. Jude investigators.

    Overactive gene increases leukemia risk

    St. Jude researchers have discovered that a gene can contribute to gross overproduction of certain white blood cells, causing a disorder called myeloproliferative disease and contributing to the development of acute lymphoblastic leukemia.

    Fusion gene can cause leukemia

    A mutation caused by the fusion of two genes makes mice vulnerable to the cancer-causing effects of a second cancer-causing event.

    Chromosomes changing places

    Like substitute teachers who nab errant chair-swappers, St. Jude scientists are becoming savvy to the antics of chromosomes.

    Watching a gene combo cause cancer

    Two genes cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma.

    Gene causing cell suicide key in development of skeletal muscle

    Investigators at St. Jude Children's Research Hospital have discovered that a protein causing mature cells to commit suicide also helps primitive muscle cells called myoblasts fuse together, allowing them to develop into muscles...