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A gene called N-Myc leads a double life in certain white blood cells when it is overexpressed, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a study done by St. Jude investigators.
St. Jude researchers have discovered that a gene can contribute to gross overproduction of certain white blood cells, causing a disorder called myeloproliferative disease and contributing to the development of acute lymphoblastic leukemia.
A mutation caused by the fusion of two genes makes mice vulnerable to the cancer-causing effects of a second cancer-causing event.
Like substitute teachers who nab errant chair-swappers, St. Jude scientists are becoming savvy to the antics of chromosomes.
Two genes cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma.
Investigators at St. Jude Children's Research Hospital have discovered that a protein causing mature cells to commit suicide also helps primitive muscle cells called myoblasts fuse together, allowing them to develop into muscles...