Doralina Anghelescu, MD
Doralina Anghelescu, MD

Doralina Anghelescu, MD

Member, St. Jude Faculty

  • Director, Pain Management Service




MD – Bucharest University School of Medicine, Romania
Certificate in Business Administration – American Society of Anesthesiologists
Certification in Palliative Care Education and Practice – Harvard Medical School Center for Palliative Care

Research Interests

  • Neuropathic pain during treatment of acute lymphoblastic leukemia
  • Vaso-occlusive crisis pain in patients with sickle cell disease
  • Neuropathic pain after limb sparing surgery in patients with osteosarcoma
  • Safety of outpatient patient controlled analgesia
  • Patient controlled analgesia at the end of life
  • Pain management at the end of life and palliative sedation
  • Impact of psychological interventions for pain management during monoclonal antibodies infusions for pediatric cancer
  • Opioid abuse and misuse risk assessment and mitigation strategies

Selected Publications

Anghelescu DL. The Use of Electronic Health Records in a Pediatric Pain Practice. The Pain Practitioner 2013.

Anghelescu DL, Ehrentraut JH, Faughnan, LG. Opioid Misuse and Abuse: Risk Assessment and Management in Patients with Cancer Pain. J Natl Compr Canc Netw 11(8):1023-31, 2013.

Anghelescu DL, Burgoyne LL, Faughnan LG, Hankins GM, Smeltzer MP, Pui CH. Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer. J Pediat 162(1):137-41, 2013. Epub 2012 Aug 9.

Burgoyne LL, Pereiras, LA, Faughnan LG, Parrish ME, Bertani LA, Kaddoum RN, Neel M, Anghelescu DL. Long Term use of Nerve Block Catheters in Pediatric Patients with Cancer Related Pathologic Fractures. Anaesth Intensive Care 40(4):710-3, 2012.

Anghelescu DL, Faughnan LG, Oakes LL, Windsor KB, Pei D, Burgoyne LL. Parent Controlled Analgesia for Pain Management in Pediatric Oncology: Is it Safe? J Pediatr Hematol Oncol 34(6):416-20 2012.

Anghelescu DL, Hamilton HD, Faughnan LG, Johnson, L-M, Baker JN. Pediatric Palliative Sedation Therapy with Propofol: Recommendations Based on Experience in Children with Terminal Cancer. J Palliat Med 15(10):1082-9 20120. Epub 2012 Jun 25.

Anghelescu DL, Harris B, Faughnan LG, Oakes LL, Windsor KB, Wright BB, McCullers, JA. Risk of catheter-associated infection in young hematology/oncology patients receiving long-term peripheral nerve blocks. Paediatr Anaesth May 15, 2012. Epub ahead of print.

Kaddoum RN, Anghelescu DL, Parish ME, Wright, BB, Trujillo L, Wu J, Wu Y, Burgoyne LL. A randomized controlled trial comparing the AccuVein AV300 device to standard insertion technique for intravenous cannulation of anesthetized children. Paediatr Anaesth 22(9):884-9, 2012. Epub Jun 14, 2012.

Anghelescu DL, Faughnan LG, Popenhagen MP, Oakes LL, Pei D, Burgoyne LL. Neuropathic Pain Referrals to a Multidisciplinary Pediatric Cancer Pain Service. Pain Management Nursing 2012. DOI: 10.1016/j.pmn.2012.07.006

Anghelescu DL, Kaddoum RN, Oakes LL, Windsor KB, Faughnan LG, Burgoyne LL. An update: the safety of patient-controlled analgesia by proxy for pain management in pediatric oncology: 2004 to 2010. Anesth Analg 113(6):1525-6, 2011.

Anghelescu DL, Faughnan LG, Hankins GM, Ward DA, Oakes LL. Methadone use in children and young adults at a cancer center: a retrospective study. J Opioid Manag 7(5):353-61, 2011.

Trujillo L, Anghelescu D, Bikhazi G. Unilateral hypoglossal nerve injury caused by a laryngeal mask airway in an infant. Paediatr Anaesth 21(6):708-9, 2011.

Anghelescu DL, Rakes LC, Shearer JR, Bikhazi GB. Prevention of emergence agitation in seven children receiving low dose ketamine and propofol total intravenous anesthesia. AANA Journal 79(3):238-42, 2011.

Oakes LL, Anghelescu DL, Windsor KB, Barnhill PD, Faughnan LG. An update: institutional quality improvement initiative for pain management for pediatric cancer inpatients, 2007-2010. J Pain Symptom Manage February 26, 2011.

Anghelescu DL, Faughnan LG, Jeha S, Relling MV, Hinds PS, Sandlund JT, Cheng C, Pei D, Hankins G, Pauley JL, Pui CH. Neuropathic pain during treatment for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 57(7):1147-53, 2011.

Anghelescu DL, Oakes LL, Hankins GM. Treatment of Pain in Children after Limb-Sparing Surgery: An Institution's 26-year Experience. Pain Management Nursing 12(2):82-94, 2011.

Oakes LL, Faughnan LG, Anghelescu DL. Development of an Evidence-based Pediatric Pain Practice at St. Jude Children's Research Hospital: A 20 Year Process. 2010.

Anghelescu DL, Faughnan LG, Baker JN, Yang J, Kane JR. Use of epidural and peripheral nerve blocks at the end of life in children and young adults with cancer: the collaboration between a pain service and a palliative care service. Paediatr Anaesth 20(12):1070-7, 2010.

Swarm R, Abernethy AP, Anghelescu DL, Benedetti C, Blinderman CD, Boston B, Cleeland C, Coyle N, Deleon-Casasola OA, Eilers JG, Ferrell B, Janjan NA, Karver SB, Levy MH, Lynch M, Moryl N, Murphy BA, Nesbit SA, Oakes L, Obbens EA, Paice JA, Rabow MW, Syrjala KL, Urba S, Weinstein SM. Adult Cancer Pain. J Natl Compr Canc Netw 8(9):1046-86, 2010.

Hoffer FA, Daw NC, Xiong X, Anghelescu D, Krasin M, Yan X, Davidoff AM, Furman WF, Rodriguez-Galindo C, Spunt SL A phase I pilot study of radiofrequency ablation for the treatment of recurrent pediatric solid tumors. Cancer 115(6):1328-37, 2009.

Anghelescu DL, Burgoyne LL, Liu W, Hankins GM, Cheng C, Beckham PA, Shearer J, Norris AL, Kun LE, Bikhazi GB. Safe anesthesia for radiotherapy in pediatric oncology: St. Jude Children's Research Hospital experience, 2004-2006. Int J Radiat Oncol Biol Phys 71(2):491-7, 2008.

Baker JN, Anghelescu DL, Kane JR. Pain still lords over children. J Pediatr 152(1):6-8, 2008.

Burgoyne LL, Anghelescu DL. Intervention steps for treating laryngospasm in pediatric patients. Pediatr Anaesthesth 18(4):297-302, 2008.

Anghelescu DL, Burgoyne LL, Khun RB. Multiple mechanisms of postoperative brachial plexus injury. Anaesth Intensive Care 36(2):276-8, 2008.

Anghelescu DL, Burgoyne LL., Liu W, Hankins GM, Cheng C, Beckham PA, Shearer J, Norris AL, Kun LE, Bikhazi GB. Safe Anesthesia for Radiatiotherapy in Pediatric Oncology: St. Jude Children’s Research Hospital Experience, 2004-2006. Int J Radiat Oncol Biol Phys Jan 17, 2008.

Oakes LL, Anghelescu DL, Windsor KB, Barnhill D. An Institutional Quality Improvement Initiative for Pain Management for Pediatric Cancer Inpatients. J Pain Symptom Manage 35(6):569-656, 2008.

Anghelescu DL, Ross CE, Oakes LL, Burgoyne LL. The Safety of Concurrent Administration of Opioids via Epidural and Intravenous Routes for Postoperative Pain in Pediatric Oncology Patients. J Pain Symptom Manage 35(4):412-19, 2008.

Swarm R, Anghelescu DL, Benedetti C, Boston B, Cleeland C, Coyle N, Deleon-Casasola OA, Eidelman A, Eilers JG, Ferrell B, Grossman SA, Janjan NA, Levy MH, Lynch M, Montana GS, Nesbit S, Oakes L, Obbens EA, Paice J, Syrjala KL, Urba S, Weinstein SM. Adult cancer pain. J Natl Compr Canc Netw 5(8):726-51, 2007.

Anghelescu D, Burgoyne L, Li C-H, Liu T, Pui C-H, Hudson M, Furman W, Sandlund JT. Clinical and Diagnostic Imaging Factors Predict Anesthetic Complications in Children With Malignant Mediastinal Masses. Pediatr Anaesth 17(11):1090-8, 2007.

Pershad J, Wan J, Anghelescu DL. Comparison of propofol with pentobarbital/midazolam/fentanyl for magnetic resonance imaging of the brain in children. Pediatrics 120(3):629-36, 2007.

Last update: March 2015