Rebekah Baskin, PhD

Rebekah Baskin, PhD

  • Senior Research Technologist

Departments

Divisions

Education

BS - Georgia Southern University
PhD
- University of Florida

Honors and Awards

  • 2008-2011  Grinter Award Fellowship, University of Florida College of Medicine
  • 2008-2012  Alumni Graduate Fellowship, University of Florida College of Medicine

Research Interests

I am interested in studying mechanisms of genetic predisposition to cancer. Understanding the functional consequences of cancer risk variants will allow us to improve therapeutic strategies.

Selected Publications

Buckley M, Gjyshi A, Mendoza-Fandino G, Baskin R, Carvalho RS, Carvalho MA, Woods NT, Monteiro AN. Enhancer scanning to locate regulatory regions in genomic loci. Nature Protocols 11:46-60, 2016.

Baskin R, Woods NT, Mendoza-Fandino G, Forsyth P, Egan KM, Monteiro AN. Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility. Scientific reports 5:17367, 2015.

Egan KM, Baskin R, Nabors LB, Thompson RC, Olson JJ, Browning JE, Madden MH, Monteiro AN. Brain tumor risk according to germ-line variation in the MLLT10 locus. European journal of human genetics. EJHG 23:132-134, 2015.

Baskin R, Park SO, Keseru GM, Bisht KS, Wamsley HL, Sayeski PP. The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo. PloS One 9:e105568, 2014.

Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth. Experimental Hematology 40:22-34, 2012.

Baskin R, Sayeski PP. Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1. Cellular Signalling 24:435-442, 2012.

Baskin R, Gali M, Park SO, Zhao ZJ, Keseru GM, Bisht KS, Sayeski PP. Identification of novel SAR properties of the Jak2 small molecule inhibitor G6: significance of the para-hydroxyl orientation. Bioorganic & Medicinal Chemistry Letters 22:1402-1407, 2012.

Majumder A, Govindasamy L, Magis A, Kiss R, Polgar T, Baskin R, Allan RW, Agbandje-McKenna M, Reuther GW, Keseru GM, et al. Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core. The Journal of Biological Chemistry 285:31399-31407, 2010.

Baskin R, Majumder A, Sayeski PP. The recent medicinal chemistry development of Jak2 tyrosine kinase small molecule inhibitors. Current Medicinal Chemistry 17:4551-4558, 2010.

Last update: January 2016