Eric J. Enemark, PhD
Eric J. Enemark, PhD

Eric J. Enemark, PhD

Associate Member, St. Jude Faculty



BA – Carleton College, Northfield, MN (1991)
PhD – Stanford University, Stanford, CA (1999)

Research Interests

Molecular mechanisms of DNA replication:

  • Atomic details underlying molecular recognition and site-specific DNA-binding
  • Molecular details of DNA manipulation and translocation
  • The role of ATPases and their chemical architecture 

Selected Publications

Enemark EJ, Joshua-Tor L. Helicases and other Molecular Motors. Current Opinion in Structural Biology 18:243-257, 2008.

Enemark EJ, L. Joshua-Tor L. Mechanism of DNA translocation in a replicative hexameric helicase. Nature 442:270-275, 2006.

Tolia NH, Enemark EJ, Sim BKL, Joshua-Tor L. Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell 122:183-193, 2005.

Enemark EJ, Stenlund A, Joshua-Tor L. Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex. EMBOJ 21:1487-1496, 2002.

Enemark EJ, Chen G, Vaughn DE, Stenlund A, Joshua-Tor L. Crystal Structure of the DNA Binding Domain of the Replication Initiation Protein E1 from Papillomavirus. Molec Cell 6:149-158, 2000.

Enemark EJ, Stack TDP. Stereospecificity and Self-Selectivity in the Generation of a Chiral Molecular Tetrahedron by Metal-Assisted Self-Assembly. Angew Chem Int Ed Engl 37:932-935, 1998.

Masood MA, Enemark EJ, Stack TDP. Ligand Self-Recognition in the Self-Assembly of a [{Cu(L)}2]2 Complex: The Role of Chirality. Angew Chem Int Ed Engl 37:928-932, 1998.

Enemark EJ, Stack TDP. Spectral and Structural Characterization of Two Ferric Coordination Modes of a Simple Bis(catecholamide) Ligand: Metal-Assisted Self-Assembly in a Siderophore Analog. Inorganic Chemistry 35:2719-2720, 1996.

Enemark EJ, Stack TDP. Synthesis and Structural Characterization of a Stereospecific Dinuclear Gallium Triple Helix: Use of the trans-Influence in Metal-Assisted Self-Assembly. Angew Chem Int Ed Engl 34:996-998, 1995.

Last update: February 2013