Charles Gawad, MD, PhD
Charles Gawad, MD, PhD

Charles Gawad, MD, PhD

Assistant Member, St. Jude Faculty

Departments

Divisions

Education

BS – Arizona State University
MD – University of Arizona
PhD – Stanford University
Postdoctoral Training – Stanford University

Honors & Awards

  • 2015-2020  Burroughs Wellcome Fund, Career Award for Medical Scientists
  • 2015-2018  Hyundai Scholar, Hyundai Foundation for Pediatric Cancer Research
  • 2013-2015  American Society of Hematology Fellow Scholar, Basic Science
  • 2013  ASH-EHA Translational Research Training in Hematology
  • 2013-2016  Leukemia and Lymphoma Society Special Fellow
  • 2011-2015  Advanced Residency Training at Stanford
  • 2003-2005  Research Training Fellowship for Medical Students HHMI
  • 2002-2003  Research Scholars Program HHMI-NIH

Research Interests

  • Using single-cell genomics to dissect the roles of intratumor heterogeneity in cancer biology
  • Understanding how pediatric leukemias develop
  • Genomics technology development for basic science and clinical applications

About the Gawad lab

Selected Publications

Gawad C, Koh W, Quake SR.  Single-cell genome sequencing: current state of the science. Nat Rev Genet 17(3):175-188, 2016. PMID: 26806412.

Koh, W, Gonzalez V, Natarajan S, Carter R, Brown PO, Gawad C. Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells. PLoS One 11(10);e0164085, 2016. PMID: 27736885.

Priest JR, Gawad C, Kahlig KM, Yu JK, O’Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, Grove M, Perez MV, Neff NF, Chen R, Maeda K, Dubin A, Belardinelli L, West J, Antolik C, Macaya D, QuertermousT, Trayanova NA, Quake SR, Ashley EA.  Early somatic mosaicism is a rare cause of long-QT syndrome. Proc Natl Acad Sci USA 113(41) 11555-11560, 2016. PMID: 27681629.

Gawad C, Koh W, Quake SR. Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc Natl Acad Sci USA 111(50):17947-52, 2014. PMID: 25425670.

de Bourcy C, De Vlaminck I, Kanbar J, Wang J, Gawad C, Quake SR. A quantitative comparison of single-cell whole genome amplification methods. PLoS One 9(8):e105585, 2014. PMID: 25136831.

Koh W, Pan W, Gawad C, Fan C, Blumenfeld Y, El-Sayed Y, Quake SR. Noninvasive in vivo monitoring of tissue-specific global gene expression in humans. Proc Natl Acad Sci USA 111:7361-6, 2014. PMID: 24799715.

Gawad C, Pepin F, Carlton V, Klinger M, Logan A, Miklos D, Faham M, Dahl G, Lacayo N. Massive evolution of immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia. Blood 120(22): 4407-17, 2012. PMID: 22932801.

Salzman J, Gawad C, Wang P, Lacayo N, Brown PO. Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PLoS One 7(2): e30733, 2012. PMID: 22319583.

Gawad C. Towards molecular medicine: a case for a biological periodic table. American Journal of Pharmacogenomics 5(4):207-211, 2005. PMID: 16078857.

Last update: October 2016