Akinobu Kamei, MD
Akinobu Kamei, MD

Akinobu Kamei, MD

Research Associate, St. Jude Faculty

Departments

Education

MD – Keio University, Tokyo, Japan

Honors & Awards

  • 2011-2013 Pediatric Infectious Diseases Society, St. Jude Fellowship Award in Basic Science

Research Interests

  • Innate and adaptive immunity to Pseudomonas aeruginosa
  • Development of new preventive/therapeutic strategies for infectious diseases in neutropenic cancer patients

Selected Publications

Kamei A, Gao G, Neale G, Loh LN, Vogel P, Thomas PG, Tuomanen EI, Murray PJ. Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy. Proc Natl Acad Sci U S A 113(41), 2016. Sep 26. pii: 201607787. [Epub ahead of print] PMID:27671632

González-Juarbe N, Gilley RP, Hinojosa CA, Bradley KM, Kamei A, Gao G, Dube PH, Bergman MA, Orihuela CJ. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog Dec 11;11(12):e1005337, 2015.. doi: 10.1371/journal.ppat.1005337. eCollection 2015 Dec. PMID:26659062

Kamei A, Wu W, Traficante DC, Koh AY, Van Rooijen N, Pier GB, Priebe GP. Collaboration between macrophages and vaccine-Induced CD4+ T Cells confers protection against lethal Pseudomonas aeruginosa pneumonia during neutropenia. J Infect Dis 207(1):39-49, 2013. PMCID: PMC3523801.

Kamei A, Coutinho-Sledge YS, Goldberg JB, Priebe GP, Pier GB. Mucosal vaccination with a multivalent, live-attenuated vaccine induces multifactorial immunity against Pseudomonas aeruginosa acute lung infection. Infect Immun 79(3):1289-1299, 2011. PMCID: PMC3067523.

Koh AY, Mikkelsen PJ, Smith RS, Coggshall KT, Kamei A, Givskov M, Lory S, Pier GB. Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination. PLoS One 5(12):e15131, 2010. PMCID: PMC3000825.

Kamei A, Koh AY, Gadjeva M, Priebe GP, Lory S, Pier GB. Analysis of acquisition of Pseudomonas aeruginosa Gastrointestinal mucosal colonization and horizontal transmission in a murine model. J Infect Dis 201(1):71-80. 2010. PMCID: PMC2791183.

Priebe GP, Walsh RL, Cederroth TA, Kamei A, Coutinho-Sledge YS, Goldberg JB, Pier GB. IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strain of Pseudomonas aeruginosaJ Immunol 181(7):4965-4975, 2008. PMCID: PMC2597098.

Last update: October 2016