Robert J. Ogg, PhD
Robert J. Ogg, PhD

Robert J. Ogg, PhD

Associate Member, St. Jude Faculty

  • Chief, Translational Imaging Research Division




BS – Old Dominion University, Norfolk, Virginia
MS – George Washington University, Washington, DC
PhD – University of Virginia, Charlottesville

Research Interests

  • Biomedical NMR Imaging and Spectroscopy
  • Functional Neuroimaging
  • Brain Function in Survivors of Catastrophic Diseases of Childhood
  • Diagnostic Imaging in Pediatric Oncology 

Selected Publications

Barb SM, Rodriguez-Galindo C, Wilson MW, Phillips NS, Zou P, Scoggins MS , Li Y, Qaddoumi I, Helton KJ, Bikhazi G, Haik BG, Ogg RJ. Functional Neuroimaging to Characterize Visual System Development in Children with Retinoblastoma. Investigational Ophthalmology and Visual Science 52:2619-2626, 2011.

Broadway J, Ogg RJ, Scoggins MA, Sanford RA Patay Z, Boop FA. Diffusion Tensor Imaging Improves Planning for Resection of Thalamopeduncular Astrocytomas of Childhood. J Neurosurg Pediatrics 7:589-595, 2011.

Hua C, Merchant TE, Gajjar A, Broniscer A, Zhang Y, Li Y, Glenn GR, Kun LE, Ogg RJ. Brain tumor therapy-induced changes in normal appearing brainstem measured with longitudinal diffusion tensor imaging. Int J Radiat Oncol Biol, 2011.

Zou P, Helton KJ, Smeltzer M, Li CS, Conklin HM, Gajjar A, Wang WC, Ware RE, Ogg RJ. Hemodynamic responses to visual stimulation in children with sickle cell anemia. Brain Imaging and Behavior 5(4):295-306, 2011.

Gibson P, Tong Y, Robinson G, Thompson M, Currle DS, Eden C, Hogg T, Martin J, Lee Y, Zindy F, Finkelstein D, Pounds S, Patay Z, Scoggins MA, Ogg RJ, Lindsey JC, Gutmann DH, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel M, McKinnon PJ, Taketo MM, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Subtypes of medulloblastoma have distinct developmental origins. Nature, 2010.

Palmer SL, Reddick WE, Glass JO, Ogg R, Patay Z, Wallace D, Gajjar A. Regional white matter anisotropy and reading ability in patients treated for pediatric embryonal tumors. Brain Imaging Behav March 9, 2010.

Morris EB, Phillips NS, Laningham FH, Patay Z, Gajjar A, Wallace D, Boop F, Sanford R, Ness KK, Ogg RJ. Proximal dentatothalamocortical tract involvement in posterior fossa syndrome. Brain 132(11):3087-3095, 2009.

Ogg RJ, Laningham FH, Clarke D, Einhaus S, Zou P, Tobias ME, Boop FA. Passive range of motion functional magnetic resonance imaging localizing sensorimotor cortex in sedated children Clinical article. J Neurosurg Pediatrics 4(4)317-322, 2009.

Fulton SP, Clarke DF, Wheless JW, Ellison DW, Ogg R, Boop FA. Angiocentric glioma-induced seizures in a 2-year-old child. J Child Neurol 24(7): 852-856, 2009.

Helton KJ, Paydar A, Glass J, Weirich EM, Hankins J, Hankins G, Zou P, Li C-S, Smeltzer MP, Wang WC, Ware RE, Reddick WE, Ogg RJ. Arterial Spin-Labeled Perfusion Combined with Segmentation Techniques to Evaluate Cerebral Blood Flow in White and Gray Matter of Children with Sickle Cell Anemia. Pediatric Blood and Cancer 52(1):85-91, 2008.

Iftekharuddin KM, Zheng J, Islam MA, Ogg RJ. Fractal-based brain tumor detection in multimodal MRI. Applied Mathematics and Computation 207(1):23-41, 2008.

Conklin HM, Li C, Xioing X, Ogg RJ, Merchant TE. Predicting Change in Academic Abilities after Conformal Radiation Therapy for Localized Ependymoma. Journal of Clinical Oncology 26(24):3965-3970, 2008.

Zhang Y, Zou P, Butler RJ, Mulhern RK, Laningham FH, Ogg RJ. Brain Structural Abnormalities in Survivors of Posterior Fossa Brain Tumors: a Voxel-Based Morphometry Study Using Free-Form Deformation. NeuroImage 42(1):218-229, 2008.

Islam A, Iftekharrudin KM, Ogg RJ, Laningham FH, Sivakumar B. Multifractal modeling, segmentation, prediction and statistical validation of posterior fossa tumors. Proceedings of SPIE 6915: 2008 (in press).

Helton KJ, Weeks JK, Phillips NS, Zou P, Kun LE, Khan RB, Gajjar AJ, Fouladi M, Li C-S, Ogg RJ. Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts. J Neurosurg Pediatrics 1(4):270-276, 2008.

Ogg RJ, Zou P, Allen DN, Hutchins SB, Dutkiewicz RM, Mulhern RK. Neural Correlates of a Clinical Continuous Performance Test. Magn Reson Imag 26(4):504-512, 2008.

Laningham FH, Kun LE, Reddick WE, Ogg RJ, Morris EB, Pui CH. Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae. Neuroradiology 49(11):873-888, 2007.

Iftekharuddin KM, Zheng J, Islam MA,. Ogg RJ, Lanningham F. Brain Tumor Detection in MRI: Technique and Statistical Validation. IEEE Proc. Fortieth Asilomar Conference on Signals, Systems and Computers 1983 – 1987, 2006.

Krasin MJ, Xiong X, Reddick WE, Ogg RJ, Hoffer FA, McCarville B, Kaste SC, Spunt SS, Navid F, Davidoff AM, Zhang  L, Kun LE, Merchant TE. A Model Predicting Radiation-Induced Quantitative Changes in the Magnetic Resonance Signal Characteristics in the Muscle of Children Over Time. Magnetic Resonance Imaging 24:1319-1324, 2006.

Shan ZY, Parra C, Ji Q, Ogg RJ, Zhang Y, Laningham FH, Reddick WE. A digital pediatric brain structure atlas from T1-weighted MR images. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv 9(2):332-339, 2006.

Helton KJ, Phillips, NS, Sanford RA, Gajjar A, Boop FA, Zou P, Langston JW, Ogg RJ. Diffusion tensor imaging of tract involvement in children with pontine tumors. AJNR Am J Neuroradiol 27(4):786-793, 2006.

Shan ZY, Parra C, Ji Q, Ogg RJ, Zhang Y, Laningham FH, Reddick WE. A digital pediatric brain structure atlas from T1-weighted MR images. Prog Biomed Opt Imaging - Proc SPIE 6141, 2006.

Iftekharuddin KM, Islam MA, Shaik J, Parra C, Ogg R. Automatic brain tumor detection in MRI: Methodology and statistical validation. Prog Biomed Opt Imaging - Proc SPIE 5747(3):2012-22, 2005.

Phillips NS, Sanford RA, Helton KJ, Boop FA, Zou P, Tekautz T, Gajjar A, Ogg RJ. Diffusion tensor imaging of intraaxial tumors at the cervicomedullary and pontomedullary junctions. Report of two cases. J Neurosurg 103(6): 557-562, 2005.

Ogg RJ, McDaniel B, Wallace D, Pitot, P, Neel MD, Kaste SC. MR safety and compatibility of a noninvasively expandable total-joint endoprosthesis. Magnetic Resonance Imaging 23(7):789-794, 2005.

Zou P, Hutchins SB, Dutkiewicz RM, Li C-S, Ogg RJ. Effects of EPI readout bandwidth on measured activation map and BOLD response in fMRI experiments. NeuroImage  27(1):15-25, 2005.

Haacke EM, Cheng NYC, Liu Q, Neelavalli J, Ogg RJ, Kahn A, Kahn A, Obenaus A, Kirsch W, Brown RW. Imaging Iron Stores in the Brain using Magnetic Resonance Imaging. Magnetic Resonance Imaging 23(1):1-25, 2005.

Steen RG, Ogg RJ. Abnormally high levels of brain N-acetylaspartate in children with sickle cell disease measured by proton magnetic resonance spectroscopy. American Journal of Neuroradiology 26(3):463-468, 2005.

Zou P, Mulhern RK, Butler RW, Li C-S, Langston JW, Ogg RJ. BOLD Responses to Visual Stimulation in Childhood Cancer Survivors. NeuroImage 24(1):61-69, 2005.

Show More

Ogg RJ, Kingsley PB. Optimized Precision of Inversion-Recovery T1 Measurements for Constrained Scan Time. Magn Reson Med 51(3):625-630, 2004.

Ries M, Boop F, Zou P, Phillips N, Johnson S, Helton, K, Ogg R. fMRI and Wada testing for language lateralization: a case of crossed dominance. Epilepsia 45(1):85-89, 2004.

DiBiance FA, Ogg RJ. Biomedical Engineering in the 21st Century: Medical Imaging. BMES Bulletin 24 (2): 5-10, 2000.

Steen RG, Reddick WE, Ogg RJ. More that meets the eye: significant regional heterogeneity in human cortical T(1). Magn Reson Imag 18(4):361-368, 2000.

Ogg RJ, Langston JW, Haacke EM, Steen RG, Taylor JS.  The Correlation Between Phase Shifts in Gradient-Echo MR Images and Regional Brain Iron Concentration. Magn Reson Imag 17(8):1141-1148, 1999.

Steen RG, Langston JW, Ogg RJ, Xiong X, Wang WC. Diffuse T1 reduction in gray matter of sickle cell disease patients: evidence of selective vulnerability to damage? Magn Reson Imag 17:503-515, 1999.

Ogg RJ, Langston JW, Haacke EM, Steen RG, Taylor JS. The correlation between phase shifts in gradient-echo MR images and regional brain iron concentration. Magn Reson Imag 17(8):1141-1148, 1999.

Steen RG, Reddick WE, Ogg RJ, Langston JW. Effect of a gadodiamide contrast agent on brain tissue T1. Magn Reson Imaging 17:229-235, 1999.

Ogg RJ, Steen RG. Age-related changes in brain T1 are correlated with iron concentration. Magnetic Resonance in Medicine 40(5):749-753, 1998.

Taylor JS, Ogg RJ, Langston JW. Proton MR spectroscopy of pediatric brain tumors. Neuroimaging Clinics of North America 8(4):753-779, 1998.

Kingsley PB, Ogg RJ, Steen RG, Reddick, WE. Correction of errors caused by imperfect inversion pulses in MR imaging measurement of T1 relaxation times. Magn Reson Imag 16:1049-1055, 1998.

Taylor JS, Ogg RJ, Langston JL. Proton MR Spectroscopy of Pediatric Brain Tumors. Mauricio Castillo, MD, ed. Neuroimaging Clinics of North America issue on Proton Spectroscopy of Brain. W. B. Saunders Company 8(4):753-779, 1998.

Ogg RJ, Steen RG. Age-related changes in brain T1 are correlated with iron concentration. Mag Reson Medicine 40:749-753, 1998.

Steen RG, Reddick WE, Mulhern RK, Langston JW, Ogg RJ, Bierberich AA, Kingsley PB, Wang WC. Quantitative MRI of the brain in children with sickle cell disease reveals abnormalities unseen by conventional MRI. J Magn Reson Imaging 8:535-543, 1998.

Steen RG, Langston JW, Ogg RJ, Manci E, Mulhern RK, Wang WC. Ectasia of the basilar artery in children with sickle cell disease: relationship to hematocrit and psychometric measures. J Stroke Cerebrovasc Dis 7:32-43, 1998.

Cho S, Jones D, Reddick WE, Ogg RJ, Steen RG. Establishing norms for age-related changes in proton T1 of human brain tissue in vivo. Magn Reson Imaging 15(10):1133-1143, 1997.

Posse S, Dager SR, Richards TL, Yuan C, Ogg R, Attru AA, Mueller-Cartuer H-W, Hayes C. In vivo measurement of regional brain metabolic response to hyperventilation using magnetic resonance proton echo-planar spectroscopic imaging. Magn Reson Med 37:858-865, 1997.

Steen RG, Ogg RJ, Reddick WE, Kingsley PB. Age-related changes in the pediatric brain: quantitative MR imaging provides evidence of maturational changes during adolescence. Am J Neuroradiol 18(5):819-828, 1997.

Taylor JS, Langston JW, Reddick WE, Kingsley PB, Ogg RJ, Pui MH, Kun LE, Jenkins JJ, Chen G, Ochs J, Sanford RA, Heideman RL. Clinical value of proton MR spectroscopy for differentiating recurrent or residual brain tumor from delayed cerebral necrosis. Int J Radiat Oncol Biol Phys 36:1251-1261, 1996.

Steen RG, Langston JW, Reddick WE, Ogg RJ, Chen G, Wang WC. Quantitative magnetic resonance imaging (qMRI) of children with sickle cell disease: Striking T1 elevation in the thalamus. J Magn Reson Imaging 6(1):226-234, 1996.

Reddick WE, Ogg RJ, Steen RG, Taylor JS. Statistical error mapping for reliable quantitative T1 imaging. J Magn Reson Imaging 6(1):244-249, 1996.

Ogg RJ, Kingsley PB, Taylor JS. WET, a T1- and B1-insensitive water-suppression method for in vivo localized 1H NMR spectroscopy. Journal of Magnetic Resonance Series B 104:1-10, 1994.

Last update: January 2012