John T. Sandlund, MD
John T. Sandlund, MD

John T. Sandlund, MD

Member, St. Jude Faculty

  • Medical Director, Leukemia / Lymphoma Clinic
  • Medical Director, Russia Program, St. Jude Global




MD – Ohio State University College of Medicine, Columbus, OH

Research Interests

  • The non-Hodgkin lymphomas
  • c-Myc regulation in Burkitt lymphoma
  • Acute leukemias

Selected Publications

Pui CH, Pei D, Pappo AS, Howard SC, Cheng C, Sandlund JT, Furman WL, Ribeiro RC, Spunt SL, Rubnitz JE, Jeha S, Hudson MM, Kun LE, Merchant TE, Kocak M, Broniscer A, Metzger ML, Downing JR, Leung W, Evans WE, Gajjar A. Treatment outcomes in black and white children with cancer: Results from the SEER Database and St. Jude Children’s Research Hospital, 1992 through 2007. J Clin Oncol 2012. PMCID: PMC3383176.

Leung W, Pui CH, Coustan-Smith E, Yang J, Pei D, Gan K, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Shook D, Rubnitz JE, Sandlund JT, Jeha S, Inaba H, Ribeiro RC, Handgretinger R, Laver JH, Campana D. Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood 2012. PMCID: PMC3398757.

Liu C, Kawedia JD, Cheng C, Pei D, Fernandez CA, Cai X, Crews KR, Kaste SC, Panetta J, Bowman WP, Jeha S, Sandlund JT, Evans WE, Pui C-H, Relling MV: Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia. Leukemia 2012. PMID:22484422.

Sandlund JT. Burkitt lymphoma: staging and response evaluation. Br J Haematol 156(6):761-5, 2012. PMCID:PMC3292702.

Otto M, Shulkin BL, Kunda M, Sandlund JT, Snyder SE, Metzger ML. Histiocyte-rich xanthomatous pseudotumor mimicking relapse on positron emission tomography imaging in an adolescent with primary mediastinal diffuse large B-cell lymphoma. J Pediatr Hematol Oncol 34(3):232-235, 2012. PMID:22082744.

Hudson MM, Neglia JP, Woods WG, Sandlund JT, Pui CH, Kun LE, Robison LL, Green DM. Lessons from the past: Opportunities to improve childhood cancer survivor care through outcomes investigations of historical therapeutic approaches for pediatric hematological malignances. Pediatr Blood Cancer 58(3):334-343, 2012. PMCID: PMC3256299.

Inaba H, Bhojwani D, Pauley JL, Pei D, Cheng C, Metzger ML, Howard SC, Rubnitz JE, Sandlund JT, Ribeiro RC, Leung W, Campana D, Pui CH, Jeha S. Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies. Br J Haematol 156(2):275-279, 2012. PMCID: PMC3235268/

Bhojwani D, Pei D, Sandlund JT, Jeha S, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff S, Onciu M, Cheng C, Coustan-Smith E, Bowman WP, Howard SC, Metzger ML, Inaba H, Leung W, Evans WE, Campana D, Relling MV, Pui CH. ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. Leukemia 26(2):265-70, 2011. PMCID: PMC3345278.

Leung W, Campana D, Yang J, Pei D, Coustan-Smith E, Gan K, Rubnitz JE, Sandlund JT, Ribeiro RC, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Handgretinger R, Laver JH, Pui CH. High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood 118(2):223-30, 2011. PMCID: PMC3138677.

Mikkelsen TS, Sparreboom A, Cheng C, Zhou Y, Boyett JM, Raimondi SC, Panetta JC, Bowman WP, Sandlund JT, Pui CH, Relling MV, Evans WE. Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial. J Clin Oncol 2011. PMCID: PMC3107765.

Brennan RC, Helton KJ, Pei D, Cheng C, Inaba H, Metzger ML, Howard SC, Rubnitz JE, Ribeiro RC, Sandlund JT, Jeha S, Pui CH, Bhojwani D. Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol 2011. PMCID: PMC3169011.

Anghelescu DL, Faughnan LG, Jeha S, Relling MV, Hinds PS, Sandlund JT, Cheng C, Pei D, Hankins G, Pauley JL, Pui CH. Neuropathic pain during treatment for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer Feb 11, 2011. doi: 10.1002/pbc.23039. NIHMS262316.

Pui CH, Pei D, Campana D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Coustan-Smith E, Jeha S, Cheng C, Metzger ML, Bhojwani D, Inaba H, Raimondi SC, Onciu M, Howard SC, Leung W, Downing JR, Evans WE, Relling MV. Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol 29(4):386-91, 2011. PMCID: PMC3058285.

Sandlund JT, Pui CH, Mahmoud H, Zhou Y, Lowe E, Kaste S, Kun LE, Krasin MJ, Onciu M, Behm FG, Ribeiro RC, Razzouk BI, Howard SC, Metzger ML, Hale GA, Rencher R, Graham K, Hudson MM. Efficacy of high-dose methotrexate, ifosfamide, etoposide and dexamethasone salvage therapy for recurrent or refractory childhood malignant lymphoma. Ann Oncol 22(2):468-71, 2011. PMCID: PMC3030464.

McGrath-Morrow S, Rothblum-Oviatt C, Greif ML, Crawford T, Lederman H, Auwaerter P, Easley R, Loughlin GM, Sandlund JT, Carroll J, Langston C, Fan LL, Brody A. Evaluation and Management of Pulmonary Disease in Ataxia-Telangiectasia. Pediatr Pulmonol 45(9):847-59, 2010. PMID: 20583220.

Metzger ML, Hudson MM, Krasin MJ, Wu J, Kaste SC, Kun LE, Sandlund JT, Howard SC. Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients. Cancer 116(18):4376-84, 2010. PMCID: PMC2936658.

Sandlund JT, Hudson MM. Treatment Strategies for Pediatric Hodgkin Lymphoma. Nat Rev Clin Oncol 7(5): 243-44, 2010. *Non-peer-reviewed material.

Pui C-H, Pei D, Sandlund JT, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Campana D, Kun LE, Jeha S, Cheng C, Howard SC, Metzger ML, Bhojwani D, Downing JR, Evans WE, Relling MV. Long-term results of St. Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia 24(2):371-82, 2010. PMCID: PMC2820159.

Sandlund JT, Laver JH. Pediatric Oncology: methotrexate-exploring dosing and administration in ALCL. Nat Rev Clin Oncol 6(8):440-1, 2009. *Non-peer-reviewed material.

Pui C-H, Campana D, Deqing P, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Coustan-Smith E, Kun LE, Jeha S, Cheng C, Howard SC, Simmons V, Bayles A, Metzger ML, Boyett JM, Leung W, Downing JR, Evans WE, Relling MV. New England Journal of Medicine 360(26):2730-41, 2009. PMCID: PMC2754320.

Coustan-Smith E, Sandlund JT, Perkins SL, Chen H, Chang M, Abromowitch M, Campana D. Minimal residual disease detection in childhood T-cell lymphoblastic lymphoma: a children’s oncology group study. Journal of Clinical Oncology 27(21):3533-9, 2009. PMCID: PMC2717759.

Jeha S, Pei D, Raimondi SC, Onciu M, Campana D, Cheng C, Sandlund JT, Ribeiro RC, Rubnitz JE, Howard SC, Downing JR, Evans WE, Relling MV, Pui C-H. Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1. Leukemia 23(8):1406-9, 2009. PMCID: PMC2731684.

Sandlund JT, Pui C-H, Zhou Y, Behm FG, Onciu M, Razzouk BI, Hijiya N, Campana D, Hudson MM, Ribeiro RC. Effective treatment of advanced-stage childhood lymphoblastic lymphoma without prophylactic cranial irradiation: results of St Jude NHL13 study. Leukemia Jun;23(6):1127-30, 2009. PMCID: PMC2843413.

Roberson JR, Spraker HL, Shelso J, Zhou Y, Inaba H, Metzger ML, Rubnitz JE, Ribeiro RC, Sandlund JT, Jeha S, Pui C-H, Howard SC: Clinical consequences of hyperglycemia during remission induction therapy for pediatric acute lymphoblastic leukemia. Leukemia 23(2):245-250, 2009.

Sandlund JT. The Combination of Monoclonal Antibodies and Conventional Chemotherapy for Children with Malignant Lymphoma: Opportunities and Challenges. Pediatric Blood and Cancer (Highlight) Feb;52(2):150-2, 2009. PMCID: PMC2857692.

Sandlund JT, Santana VM, Hudson MM, Onciu M, Behm FG, Head D, Murry DJ, Ribeiro R, Wallace D, Rencher R, Pui C-H. Dexamethasone, High-dose Cytarabine and Carboplatin (DAC) Combination is Effective for Childhood Advanced Large Large Cell Non-Hodgkin Lymphoma. Cancer 113:782-790, 2008. PMCID: PMC2975596.

Ribeiro RC, Sandlund JT. Burkitt Lymphoma in African Children: A Priority for the Global Health Agenda. Pediatric Blood and Cancer (Highlight) 50:1125-1126, 2008.

Last update: February 2013

For updates on COVID-19, please read.