Education
MD – The University of Texas Medical School at Houston
BA – Texas A&M University
Residency – Pediatric Neurology, University of Texas at Houston
Neuro-oncology Fellowship – University of Texas, MD Anderson Cancer Center
Research Interests
- Pilocytic astrocytoma molecular and clinical classification
- Neurological outcome correlated to molecular markers, clinical and neuroimaging in childhood cancer and brain tumor survivors during and after treatment
- Visual outcome in children with optic glioma
- Childhood medulloblastoma and molecular targeted therapy
Selected Publications
Sadighi ZS, Zabrowski J, Boop FA, Broniscer A, Gajjar A, Khan RB. Clinical Characteristics and Long-term Outcome in Movement Disorder in Childhood Thalamic Tumors. Pediatr Neurol Dec;65:71-77, 2016. doi: 10.1016/j.pediatrneurol.2016.08.012. Epub 2016 Aug 22.
Brinkman, TM, Kraisin MJ, Liu W, Ojha RP, Sadighi ZS, Armstrong G, Gupta P, Kimberg C, Srivastava DK, Merchant TE, Gajjar A, Robison L, Hudson M, Krull K. Neurocognitive functioning and social attainment in adult survivors of pediatric brain tumors: Results from the St. Jude Lifetime cohort study. Journal of Clinical Oncology Apr 20;34(12):1358-67, 2016. doi: 10.1200/JCO.2015.62.2589. Epub 2016 Feb 1.
Khan RB, Sadighi ZS, Zabrowski J, Gajjar A, Jeha S. Imaging Patterns and Outcome of Posterior Reversible Encephalopathy Syndrome During Childhood Cancer Treatment. Pediatric Blood Cancer Mar;63(3):523-6, 2016. doi:10.1002/pbc.25790. Epub 2015 Oct 15.9.
Sadighi Z, Sabin ND, Hayden R, Stewart E, Pillai A. Diagnostic Clues to Human Herpesvirus 6 Encephalitis and Wernicke’s Encephalopathy after Pediatric Hematopoietic Cell Transplantation. Journal of Child Neurology 2015. pii: 0883073814560628.
Sadighi Z, Ness K, Hudson M, Morris EB, Pui CH, Howard S, Krull KR, Browne E, Crom D, Hinds P, Zhu L, Srivastava DK, Khan RB. Headache types, related morbidity, and quality of life in survivors of childhood acute lymphoblastic leukemia: a prospective cross sectional study. European Journal of Paediatric Neurology 2014. doi: 10.1016/j.ejpn.2014.06.006
Theeler BJ, Ellezam B, Sadighi ZS, Mehta V, Tran MD, Adesina AM, Bruner JM, Puduvalli VK. Adult Pilocytic Astrocytomas: Clinical Features and Molecular Analysis. Neuro-Oncology Jun;16(6):841-7, 2014. doi: 10.1093/neuonc/not246. Epub 2014 Jan 26.
Sadighi Z, Slopis J. Pilocytic Astrocytoma: a disease with evolving molecular heterogeneity. Journal of Child Neurology 2013; doi: 10.1177/0883073813476141
Sadighi Z, Vats T, Khatua S. Childhood Medulloblastoma: The Paradigm Shift in Molecular Stratification and Treatment Profile. Journal of Child Neurology 2012; doi: 10.1177/08830738-12449690
Khatua S, Sadighi Z, Pearlman M, Buchare S, Vats T. Brain Tumors in Children-Current Therapies and Newer Directions. Indian Journal of Pediatrics 2012. doi:10.1007/s12098-012-0689-9
Sadighi Z, Butler IJ, Koenig MK. Adult-onset cerebral folate deficiency. Arch Neurol 2012. doi:10.1001/archneurol.2011.3036
Last update: January 2017