Paige Tedrick, BS

Paige Tedrick, BS

  • Research Technologist

Departments

Divisions

Education

BS (cum laude) – George Mason University
Internships – Logos Technologies, INOVA Fairfax Hospital, the University of Iowa, and the Smithsonian's National Museum of Natural History

Organizations

  • 2014-present Virginia Academy of Sciences
  • 2012-2014 National society of Collegiate Scholars

Research Interests

I am a research technologist with an interest in cellular signaling and the role it has in regulation of a functioning system specifically how genetic mutations can contribute to immune dysfunction. Understanding of signaling pathways can lead to a more effective approach to create target therapeutic reagents. Current work is focused on pathogenesis of X-linked lymphoproliferative disease (XLP) and hemophagocytic lymphohistiocytosis (HLH) as well as treatment for HLH.

Selected Publications

Das R, Guan P, Sprague L, Verbist K, Tedrick P, Qi A, Cheng C, Kurachi M, Levine RL, Wherry J, Canna S, Behrens EM, Nichols K. Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis. Blood 2015 (in press).

Ruffo E, Malacarne V, Larsen SE, Das R, Patrussi L, Wülfing C, Biskup C, Kapnick SM, Verbist K, Tedrick P, Schwartzberg PL, Baldari CT, Rubio I, Nichols KE, Snow AL, Baldanzi G, Graziani A. Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1. Sci Transl Med Jan 13;8(321):321ra7, 2016. doi: 10.1126/scitranslmed.aad1565

Last update: January 2016