Santhosh Upadhyaya, MD
Santhosh Upadhyaya, MD

Santhosh Upadhyaya, MD

Instructor, St. Jude Faculty




MD – Kasturba Medical College, Manipal University, India
Pediatric Residency – Kasturba Medical College, Manipal University, India
Pediatric Residency – St. John Hospital Medical Center, Detroit, MI
Pediatric Hematology Oncology Fellowship – University of Michigan, Ann Arbor, MI
Pediatric Neuro-Oncology Fellowship  St. Jude Children’s Research Hospital, Memphis, TN

Research Interests

Clinical trials for Atypical Teratoid Rhabdoid Tumor (AT/RT) and Ependymoma- Our understanding of the process of pediatric brain tumor development has significantly enhanced in recent years due to advances in the genetic and molecular techniques used to study these tumors.  My goal is to apply these advances in formulating clinical trials to improve survival and reduce long term side effects in children with Atypical Teratoid Rhabdoid tumor (AT/RT) and Ependymoma.

Clinical Interests

  • Atypical Teratoid Rhabdoid tumor (AT/RT)
  • Ependymoma
  • Infant brain tumors

Selected Publications

Upadhyaya SA, Robinson GW, Harreld JH, Klimo PD Jr, Hoehn ME, Orr BA, Qaddoumi IA. Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases. Childs Nerv Syst Feb 1, 2018. [Epub ahead of print]

Upadhyaya SA, Ghazwani Y, Wu S, et al. Mortality in Children with Low-Grade Glioma or Glioneuronal Tumors: A Single-Institution Study. Pediatr Blood Cancer  Jan;65(1), 2018. doi: 10.1002/pbc.26717

Upadhyaya SA, Mody R, Walkovich K, Hutchinson RJ, Sandlund JT, Connelly JA. Ataxia Telangiectasia and Cancer Predisposition: Challenges in Management. J Pediatr Hematol Oncol Dec 1, 2017. [Epub ahead of print]

Upadhyaya SA, Klimo Jr P, Robinson GW. Non-Malignant Cerebrospinal Fluid Ascites in a Patient with Atypical Teratoid Rhabdoid Tumor. Oncol Res Treat 40:216-219, 2017.

Upadhyaya SA, Koschmann C, Muraszko K et al. Brainstem Low-Grade Gliomas in Children-Excellent Outcomes With Multimodality Therapy. J Child Neurol Feb;32(2):194-203, 2017.

Koschmann C, Bloom K, Upadhyaya S, Geyer, JR, Leary, SES.  Survival after relapse of medulloblastoma. J Pediatr Hematol Oncol May;38(4):269-73, 2016.

Shenoy VD, Upadhyaya S, Rao SP, Shobha KL. Mycoplasma pneumoniae Infection in Children with Acute Respiratory Infection. Journal of Tropical Pediatrics Aug;51(4):232-235, 2005.

Hebbar S, Bairy I, Nalini B, Upadhyaya S, Sarma MS, Shetty AK. Fatal case of Naegleria fowleri Meningo-encephalitis in an Infant: Case Report. Annals of Tropical Pediatrics Sep; 25(3):223-226, 2005.

Last update: February 2018