Pharmaceutical Department Residency Programs

Clinical Pharmacogenetics


St. Jude Children’s Research Hospital offers a 12-month ASHP-accredited specialized (PGY2) Residency in Clinical Pharmacogenetics. 

The purpose of the program is to prepare the resident to excel in the implementation of pharmacogenetic testing in clinical practice. The institution’s full integration of an electronic medical record that applies to inpatient and outpatient care, the comprehensive translational research programs, the highly skilled clinical pharmacy specialist team, and the strong laboratory component to the Pharmaceutical Department provide unrivalled opportunities for clinical implementation of pharmacogenetics into patient care.

St. Jude runs an institution-wide program to implement pre-emptive pharmacogenetic testing (, and the resident will assist in directing that program. The resident will provide pharmacogenetic consults in the context of a comprehensive approach to pharmaceutical care integrated into the clinical practice areas for St. Jude: general hematology / oncology, bone marrow transplantation, and ambulatory care. Training will be provided in applied pharmacokinetics, infectious diseases, nutrition support, and advanced pediatric pharmacotherapy. Each resident will work with established clinicians on interdisciplinary teams.

In addition, the resident will build pharmacogenetic clinical consults, and help develop clinical decision-support based rules for alerting clinicians of high risk gene-drug pairs to allow for genetically-guided drug dosing. The resident will be expected to write a manuscript for publication, and participate in patient education, drug information, quality improvement, and medication outcomes activities. Residents are highly involved in international efforts to implement pharmacogenetics on a broad scale via participation in CPIC (Clinical Pharmacogenetics Implementation Consortium Upon completion of the program, the resident will have the clinical skills and necessary experience to practice in the field of clinical pharmacogenetics, and to implement pharmacogenetic testing in other health-system settings.

Pharmacogenetic residents have the opportunity to learn, contribute and participate in a dynamic environment that consists of professional and technical personnel in both patient care and pharmaceutical research. Along with direct patient care responsibilities, each resident will have the opportunity to gain experience in teaching through lectures, in-services, journal club presentations and precepting pharmacy students. A teaching certificate is currently offered by the University of Tennessee College of Pharmacy. An independent research project will be carried out during the course of the residency, with presentation of the findings at a national meeting.


Longitudinal Experiences

Research project

The resident will be expected to complete a research project and present the results at a national meeting. The research project will encompass one of the following areas: laboratory performance characteristics of genotyping techniques, creation of automated pharmacogenetic consults and alerts in the medical record, clinician actions based on point-of-care pharmacogenetic alerts, patient acceptance of pharmacogenetic information, and generalizability to other clinical settings through the Pharmacogenetics Research Network.

Educational experiences

Throughout the year, the Clinical Pharmacogenetics resident will provide didactic lectures to pharmacy students and in-services to clinicians in regards to implementation of pharmacogenetics in the clinic. In addition, the resident will present at journal clubs, and may participate in the Pharmacogenetics Oversight Committee and other institutional meetings.


Number of Positions


Start Date

July 1

Application Deadline

Second Monday in January


Program Director

Kristine R. Crews, PharmD, BCPS
Mail Stop 313
St. Jude Children's Research Hospital
Pharmaceutical Department
262 Danny Thomas Place
Memphis, TN 38105-3678
Phone: (901) 595-3338
FAX: (901) 595-8869

Application Requirements

While not required for candidacy, resident applicants are strongly encouraged to interview with St Jude staff at the Professional Placement Service (PPS/CareerPharm) at the ASHP Midyear Clinical Meeting. 

All application materials must be submitted through PhORCAS.

  • Background in biological sciences and basic human genetics is recommended
  • Doctor of Pharmacy degree, successful completion of an ASHP-accredited Postgraduate Year One Pharmacy Residency, and eligible for licensure to practice pharmacy in the state of Tennessee
  • Copy of official school transcript
  • Letter of intent
  • Three (3) letters of reference
  • Completion of an onsite interview