Jeremie H. Estepp, MD
Jeremie H. Estepp, MD

Jeremie H. Estepp, MD

Assistant Member, St. Jude Faculty

  • Medical Director, Clinical Translation Program in Hematology

Departments

Divisions

Education

BA – Carson-Newman College, Jefferson City, Tennessee
MD – Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia
Internship/Residency – University of Tennessee, Le Bonheur Children’s Hospital
Fellowship (Pediatric Hematology/Oncology) – St. Jude Children’s Research Hospital

Research Interests

  • Thrombosis
  • Bleeding disorders
  • Sickle Cell Disease 

Selected Publications

Alberts NM, Badawy SM, Hodges J, Estepp JH, Nwosu C, Khan H, Smeltzer MP, Homayouni R, Norell S, Klesges L, Porter JS, Hankins JS. Development of the InCharge Health Mobile App to Improve Adherence to Hydroxyurea in Patients With Sickle Cell Disease: User-Centered Design Approach. JMIR Mhealth Uhealth. May 8;8(5):e14884, 2020. doi: 10.2196/14884.

Lebensburger JD, Gossett J, Zahr R, Wang WC, Ataga KI, Estepp JH, Kang G, Hankins JS. High bias and low precision for estimated versus measured glomerular filtration rate in pediatric sickle cell anemia. Haematologica. Feb 27, 2020. pii: haematol.2019.242156. doi: 10.3324/haematol.2019.242156. [Epub ahead of print]

Zahr RS; Hankins JS, Kang G, Li C, Wang WC, Lebensburger J, Estepp JH. Hydroxyurea prevents onset and progression of albuminuria in children with sickle cell anemia. Am J Hematol. Jan;94(1):E27-E29, 2019. doi: 10.1002/ajh.25329. Epub Nov 29, 2018.

Gartrell J, Kaste SC, Sandlund JT, Flerlage J, Zhou Y, Cheng C, Estepp J, Metzger ML. The association of mediastinal mass in the formation of thrombi in pediatric patients with non-lymphoblastic lymphomas. Pediatr Blood Cancer. Feb;67(2):e28057, 2020. doi: 10.1002/pbc.28057. Epub Nov 17, 2019.

El-Gohary Y, Fleming A, Zhang H, Estepp JH, Hankins JS, Wang W, Davidoff AM, Murphy AJ. Acute chest syndrome after splenectomy in children with sickle cell disease. J Surg Res. Oct;242:336-341, 2019. doi: 10.1016/j.jss.2019.04.077. 2019 May 23, 2019.

Zahr RS, Rampersaud E, Kang G, Weiss MJ, Wu G, Davis RL, Hankins JS, Estepp JH, Lebensburger J. Children with sickle cell anemia and APOL1 genetic variants develop albuminuria early in life. Haematologica.  Sep;104(9):e385-e387, 2019. doi: 10.3324/haematol.2018.212779. Epub Mar 19, 2019.

Claassen D, Boals M, Bowling KM, Cooper GM, Cox J, Hershfield M, Lewis S, Wlodarski M, Weiss MJ, Estepp JH. Complexities of genetic diagnosis illustrated by an atypical case of congenital hypoplastic anemia. Cold Spring Harb Mol Case Stud. Dec 17;4(6), 2018. pii: a003384. doi: 10.1101/mcs.a003384.

Mesleh Shayeb A, Smeltzer MP, Kaste SC, Brown A, Estepp JH, Nottage KA. Vaso-occlusive crisis as a predictor of symptomatic avascular necrosis in children with sickle cell disease. Pediatr Blood Cancer Sept. 5;e27435, 2018.

Hankins JS, Estepp JH, Hodges JR, Villavicencio MA, Robison LL, Weiss MJ, Kang G, Schreiber JE, Porter JS, Kaste SC, Saving KL, Bryant PC, Deyo JE, Nottage KA, King AA, Brandow AM, Lebensburger JD, Adesina O, Chou ST, Zemel BS, Smeltzer MP, Wang WC, Gurney JG. Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood. Pediatr Blood Cancer May 24;e27228, 2018.

Estepp JH. Voxelotor (GBT440), a first-in-class hemoglobin oxygen-affinity modulator, has promising and reassuring preclinical and clinical data. Am J Hematol 93(3):326-329, 2018.

Cancio MI, Aygun B, Chui DHK, Rothman JA, Scott JP, Estepp JH, Hankins JS. The clinical severity of hemoglobin S/Black (A γδβ)0 -thalassemia. Pediatr Blood Cancer Apr 28; 64:11, 2017. 

Gammal RS, Crews KR, Haidar CE, Hoffman JM, Baker DK, Barker PJ, Estepp JH, Pei D, Broeckel U, Wang W, Weiss MJ, Relling MV, Hankins J. Pharmacogenetics for safe codeine use in sickle cell disease. Pediatrics 138(1), 2016.

Estepp JH, Melloni C, Thornburg CD, Wiczling P, Rogers Z, Rothman JA, Green NS, Liem R, Brandow AM, Crary SE, Howard TH, Morris MH, Lewandowski A, Garg U, Jusko WJ, Neville KA. Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia. J Clin Pharmacol 56(3):298-306, 2015.

Estepp JH, Winter B, Johnson M, Smeltzer MP, Howard SC, Hankins JS. Improved hydroxyurea effect with the use of text messaging in children with sickle cell anemia. Pediatr Blood Cancer 61(11):2031-36, 2014.

Estepp JH, Smeltzer MP, Wang WC, Hoehn ME, Hankins JS, Aygun B. Protection from sickle cell retinopathy is associated with elevated HbF levels and hydroxycarbamide use in children. Br J Haematol 161(3):402-405, 2013.

Estepp JH, Smeltzer M, Reiss UM. The impact of quality and duration of enoxaparin therapy on recurrent venous thrombosis in children. Pediatr Blood Cancer 59(1):105-109, 2012.

 

Last update: May 2020

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