Andrew T. Kodani, PhD
Andrew T. Kodani, PhD

Andrew T. Kodani, PhD

Assistant Member, St. Jude Faculty

Departments

Divisions

Center for Pediatric Neurological Disease Research

Education

Postdoctoral Fellowship - University of California, San Francisco
PhD - University of California, Irvine
BA - University of California, Berkeley

Research Interests

  • Mechanisms underlying neurodevelopmental disorders
  • Identifying human mutations that cause microcephaly and lissencephaly
  • Developmental signaling involved in neurodevelopment
  • Host-pathogen interactions that disrupt innate immunity

Kodani Research Lab

Contact Information

Andrew T. Kodani, PhD Center for Pediatric Neurological Disease Research MS 340, Room D4007E St. Jude Children's Research Hospital 262 Danny Thomas Place Memphis, TN 38105-3678

St. Jude Faculty List

Selected Publications

Lek A, Zhang Y…Kodani A…Kunkel LM. Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in FSHD. Science Translational Medicine eaay0271, 2020.

Kodani A*, Kenny C…Walsh CA*. Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5. Neuron S0896-6273(20)30056-8, 2020. *co-corresponding author

Kodani A*, Chen A, Moyer T, Holland A, Reiter J, Walsh CA. SFI1 recruits USP9X to promote the stability of microcephaly protein STIL. Journal of Cell Biology 218(7):2185, 2019. *corresponding author

Johnson M, Sun X*, Kodani A*, Borges R*…Walsh CA. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size. Nature 2018;370-375, 2018. *co-second authors.

Zhang X, Hui Chen M, Wu X, Kodani A…Walsh CA. Cell type-specific alternative splicing governs cell fate in the developing cerebral cortex. Cell 166(5):1147-1162.e15, 2016.

Jayaraman D*, Kodani A*, Gonzalez D…Reiter J, Bae B, Yu T, Walsh CA. Wdr62 and Aspm encode mother centriole proteins that function together in centriole biogenesis and regulation of brain size. Neuron 92(4):813-828, 2016. PMID: 2794163. Cover. *co-first author

Kodani A, Yu T, Johnson JR, Jayaraman D…Krogan N, Walsh CA, Reiter J. Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. eLife 10.7554/eLife.07519, 2015.

Hu F, Pomp O*, Ben-Omran T*, Kodani A*…Reiter J, Harris MP, Reversade B, Walsh C. Katanin p80 regulates human cortical development by limiting centriole and cilia number. Neuron 84(6):1240-57, 2014. *equal contribution

Kodani A, Sirerol-Piquer MS, Seol A, Garcia-Verdugo JM, Reiter J. Kif3a interacts with Dynactin subunit p150Glued to organize centriole subdistal appendages. EMBO J 32(4):597-607, 2013.

Kodani A, Tonthat V, Wu B. Sütterlin C. The Cdc42 effector, Par6a, controls centrosome organization by regulating the localization of PCM-1. Mol Biol Cell 21(19):3376-85, 2010.

Kodani A, Sütterlin C. A new function for an old organelle: Microtubule nucleation at the Golgi apparatus. EMBO News and Views 28(8):995-6, 2009.

Kodani A, Kristensen I, Huang L, Sütterlin C. GM130-dependent Control of Cdc42 Activity at the Golgi Regulates Centrosome Organization. Mol Biol Cell 20(4):1192-1200, 2008.

Kodani A, Sütterlin C. The Golgi protein GM130 regulates centrosome morphology and function. Mol Biol Cell 19(2):745-53, 2008.

Zhou R, Zhu L, Kodani A, Hauser P, Yao X, Forte JG. Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci 118(Pt 19):4381-91, 2005.

Last update: October 2020

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