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Andrew T. Kodani, PhD
Andrew T. Kodani, PhD

Andrew T. Kodani, PhD

Assistant Member, St. Jude Faculty



Center for Pediatric Neurological Disease Research


Postdoctoral Fellowship - University of California, San Francisco
PhD - University of California, Irvine
BA - University of California, Berkeley

Research Interests

  • Mechanisms underlying neurodevelopmental disorders
  • Identifying human mutations that cause microcephaly and lissencephaly
  • Developmental signaling involved in neurodevelopment
  • Host-pathogen interactions that disrupt innate immunity

Selected Publications

Lek A, Zhang Y…Kodani A…Kunkel LM. Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in FSHD. Science Translational Medicine eaay0271, 2020.

Kodani A*, Kenny C…Walsh CA*. Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5. Neuron S0896-6273(20)30056-8, 2020. *co-corresponding author

Kodani A*, Chen A, Moyer T, Holland A, Reiter J, Walsh CA. SFI1 recruits USP9X to promote the stability of microcephaly protein STIL. Journal of Cell Biology 218(7):2185, 2019. *corresponding author

Johnson M, Sun X*, Kodani A*, Borges R*…Walsh CA. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size. Nature 2018;370-375, 2018. *co-second authors.

Zhang X, Hui Chen M, Wu X, Kodani A…Walsh CA. Cell type-specific alternative splicing governs cell fate in the developing cerebral cortex. Cell 166(5):1147-1162.e15, 2016.

Jayaraman D*, Kodani A*, Gonzalez DReiter J, Bae B, Yu T, Walsh CA. Wdr62 and Aspm encode mother centriole proteins that function together in centriole biogenesis and regulation of brain size. Neuron 92(4):813-828, 2016. PMID: 2794163. Cover. *co-first author

Kodani A, Yu T, Johnson JR, Jayaraman D…Krogan N, Walsh CA, Reiter J. Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. eLife 10.7554/eLife.07519, 2015.

Hu F, Pomp O*, Ben-Omran T*, Kodani A*…Reiter J, Harris MP, Reversade B, Walsh C. Katanin p80 regulates human cortical development by limiting centriole and cilia number. Neuron 84(6):1240-57, 2014. *equal contribution

Kodani A, Sirerol-Piquer MS, Seol A, Garcia-Verdugo JM, Reiter J. Kif3a interacts with Dynactin subunit p150Glued to organize centriole subdistal appendages. EMBO J 32(4):597-607, 2013.

Kodani A, Tonthat V, Wu B. Sütterlin C. The Cdc42 effector, Par6a, controls centrosome organization by regulating the localization of PCM-1. Mol Biol Cell 21(19):3376-85, 2010.

Kodani A, Sütterlin C. A new function for an old organelle: Microtubule nucleation at the Golgi apparatus. EMBO News and Views 28(8):995-6, 2009.

Kodani A, Kristensen I, Huang L, Sütterlin C. GM130-dependent Control of Cdc42 Activity at the Golgi Regulates Centrosome Organization. Mol Biol Cell 20(4):1192-1200, 2008.

Kodani A, Sütterlin C. The Golgi protein GM130 regulates centrosome morphology and function. Mol Biol Cell 19(2):745-53, 2008.

Zhou R, Zhu L, Kodani A, Hauser P, Yao X, Forte JG. Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci 118(Pt 19):4381-91, 2005.

Last update: October 2020