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Researchers discover how a protein complex revs up T cell activation to fight infections
12/16/2013
St. Jude Children’s Research Hospital scientists find mechanism that launches production of the specialized T cells essential for combating infectious agents and that offers new therapeutic possibilities.
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Gene sequencing project finds family of drugs with promise for treating childhood tumor
12/09/2013
St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project study identifies drugs that enhance oxidative stress as possible weapon against most common pediatric soft tissue tumor
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Gene therapy bolsters enzyme activity to combat Alzheimer’s disease in mice
12/03/2013
St. Jude Children’s Research Hospital scientists identify enzyme that could lead to better diagnosis and treatment of Alzheimer’s disease and related disorders. (Dr. Alessandra d'Azzo)
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1950s pandemic influenza virus remains a health threat, particularly to those under 50
12/02/2013
St. Jude Children’s Research Hospital scientists report that avian H2N2 influenza A viruses related to 1957-1958 pandemic infect human cells and spread among ferrets; may aid identification of emerging threats
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Drug offers promising approach to improve outcome for children with high-risk leukemia
11/15/2013
St. Jude Children’s Research Hospital leads study showing that a drug withdrawn from the market in 2010 may enhance the effectiveness of bone marrow transplants for select pediatric leukemia patients.
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St. Jude Children’s Research Hospital scientific director elected to Institute of Medicine
10/21/2013
James R. Downing, M.D., scientific director, deputy director and executive vice president at St. Jude Children’s Research Hospital, has been elected to the Institute of Medicine.
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Inherited gene variation tied to high-risk pediatric leukemia and greater risk of relapse
10/20/2013
Study led by St. Jude Children’s Research Hospital finds an inherited gene variation—more common among Hispanic Americans–is tied to increased risk of developing a high-risk form of pediatric leukemia. (Dr. Jun Yang)
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Research offers new insight in quest for single vaccine against multiple influenza strains
10/20/2013
A study led by St. Jude Children’s Research Hospital identifies new path to a universal influenza vaccine emphasizing production of broadly specific antibodies that target multiple flu viruses.
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Preventable risk factors pose serious threat to heart health of childhood cancer survivors
10/10/2013
A Childhood Cancer Survivors Study led by St. Jude Children’s Research Hospital suggests that reducing risk factors like hypertension might lower the risk of heart disease for survivors as they age.
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St. Jude Children’s Research Hospital names new chief legal officer
10/10/2013
Robyn Diaz, J.D., tapped to serve as chief legal officer and senior vice president at St. Jude Children's Research Hospital.
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St. Jude Children’s Research Hospital scientist recognized by American-Italian Cancer Foundation
10/09/2013
Charles J. Sherr, M.D., Ph.D., to receive the Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.
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St. Jude Children’s Research Hospital appoints new clinical director
09/26/2013
Larry Kun, M.D., to oversee all aspects of patient care and clinical services at St. Jude Children's Research Hospital.
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St. Jude Children’s Research Hospital CEO announces retirement
09/16/2013
Dr. William E. Evans will retire from executive post at St. Jude Children's Research Hospital in July 2014.
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Rare, inherited mutation leaves children susceptible to acute lymphoblastic leukemia
09/09/2013
Research from St. Jude Children’s Research Hospital, Memorial Sloan-Kettering Cancer Center and the University of Washington identifies a mutation that predisposes individuals to most common form of childhood leukemia.
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Drug reduces hospitalizations and cost of treating young children with sickle cell anemia
09/02/2013
The St. Jude Children’s Research Hospital-led national BABY HUG trial linked hydroxyurea to a 21 percent reduction in annual medical costs for young children with sickle cell anemia; savings expected to grow.
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St. Jude Children’s Research Hospital study yields new strategy against high-risk leukemia
08/29/2013
After identifying a protein that blocks death of high-risk acute lymphoblastic leukemia (ALL) cells, scientists use two-drug combination therapy to offer hope to children and adults with the disease.
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St. Jude Children’s Research Hospital scientists identify ALS disease mechanism
08/28/2013
Study strengthens link between amyotrophic lateral sclerosis (ALS) and problems in protein production machinery of cells and identifies possible treatment strategy.
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Understanding mutation leads to promising new treatment for autoinflammatory diseases
08/08/2013
St. Jude Children’s Research Hospital study yields clues for designing next-generation drugs to treat autoinflammatory diseases.
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St. Jude creates $5.5 million endowment for cancer research to be held by the hospital CEO
08/02/2013
The Donald Pinkel Endowed Chair of Pediatric Cancer Treatment honors first director of St. Jude and is among the largest endowed chairs in the nation.
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Protein targeted for cancer drug development is essential for normal heart function
07/10/2013
St. Jude Children's Research Hospital discovers a role for a protein in research that has implications for treatment of cancer and heart disease.
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Maintaining immune balance involves an unconventional mechanism of T cell regulation
07/03/2013
St. Jude Children's Research Hospital study challenges prior understanding of the process regulating specialized T cells that are essential for a balanced immune system.
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Childhood cancer survivors found to have significant undiagnosed disease as adults
06/11/2013
St. Jude Children’s Research Hospital study identifies the need for proactive, life-long medical follow-up and provides the most complete health picture yet of adult survivors of childhood cancer.
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Epigenetic factor likely plays a key role in fueling most common childhood cancer
06/10/2013
A study led by St. Jude Children’s Research Hospital shows epigenetic changes that turn genes on and off are as unique as alterations in DNA and may be as important in causing the most common childhood cancer.
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James Hoffman, Pharm.D., named American Society of Health-System Pharmacists fellow
05/29/2013
James Hoffman, Pharm.D., has been recognized by the American Society of Health-System Pharmacists for excellence in pharmacy practice.
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Robert Webster, Ph.D., presented with National Foundation for Infectious Diseases award
05/14/2013
Virologist Robert G. Webster, Ph.D., of St. Jude Children’s Research Hospital, is the recipient of the Charles Mérieux Award from the National Foundation for Infectious Diseases.
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St. Jude scientist named Howard Hughes Medical Institute investigator
05/09/2013
Michael Dyer, Ph.D., of St. Jude Children's Research Hospital, has been recognized as one of the nation’s leading biomedical researchers by the Howard Hughes Medical Institute.
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Charles Sherr, M.D., Ph.D., recognized as 2013 fellow of the American Academy of Arts and Sciences
04/26/2013
St. Jude Children's Research Hospital scientist Charles Sherr, M.D., Ph.D., is named a 2012 fellow of the American Academy of Arts and Sciences.
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Gene sequencing project finds new mutations to blame for a majority of brain tumor subtype
04/14/2013
The St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project advances understanding of genetic defects underlying childhood low-grade gliomas and identifies promising new drug therapies.
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St. Jude scientist named American Association for Cancer Research Academy Fellow
03/27/2013
Charles Sherr, MD, PhD, Chair of the Department of Tumor Cell Biology at St. Jude Children’s Research Hospital, is honored by the AACR Academy for his scientific contributions to advancing understanding and treatment of cancer.
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Inherited genetic variations have a major impact on childhood leukemia risk
03/19/2013
Study links inherited genetic variations in a few genes to increased risk of acute lymphoblastic leukemia (ALL) and helps to explain ethnic differences in the cancer’s incidence.
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St. Jude Children’s Research Hospital announces issuance of U.S. patent for genetically modified human immune cells for cancer therapy
03/19/2013
The United States Patent and Trademark Office today awarded St. Jude Children’s Research Hospital U.S. patent number 8,399,645 for St. Jude’s invention of compositions for genetically modifying human immune cells so they can destroy some of the most common forms of cancer in children and adults.
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Two new genes linked to amyotrophic lateral sclerosis (ALS) and related disorders
03/03/2013
St. Jude Children’s Research Hospital ties mutations in two genes to the death of motor neurons associated with ALS, or Lou Gehrig's disease, and other devastating neurodegenerative problems.
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Rise in drug costs to hospitals, clinics slowing in 2013
02/15/2013
St. Jude Children’s Research Hospital-led analysis finds rise less than in previous years; cancer drugs the exception.
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Gene sequencing project mines data once considered 'junk' for clues about cancer
01/24/2013
St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project takes new approach to measuring the repetitive DNA at the end of chromosomes and opens new window on mechanisms fueling cancer.
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Genetic basis of high-risk childhood cancer points to possible new drug treatment strategy
01/20/2013
St. Jude Children’s Research Hospital scientists lead a study that finds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss and evidence that some patients have an inherited cancer syndrome.