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Zoltán Patay, MD, PhD
Zoltán Patay, MD, PhD

Zoltán Patay, MD, PhD

Member, St. Jude Faculty

  • Chair, Diagnostic Imaging Department
  • Chief, Neuroradiology Section



MD – Semmelweis University, Medical School, Budapest, Hungary (1982)
PhD – Hungarian Academy of Sciences, Budapest, Hungary (1996)

Research Interests

  • Normal and abnormal myelination
  • Inborn errors of metabolism
  • Multimodality tumor tissue characterization
  • Diffusion-weighted and diffusion tensor imaging
  • Cerebrovascular diseases
  • Epilepsy

Selected Publications

Patay Z, Blaser SI, Poretti A, Huisman TAGM. Neurometabolic diseases of childhood. Pediatr Radiol 45(Suppl 3):S473–S484, 2015.

Harreld JH, Mohammed N, Goldsberry G, Li X, Li Y, Boop F, Patay Z. Postoperative Intraspinal Subdural Collections after Pediatric Posterior Fossa Tumor Resection: Incidence, Imaging, and Clinical Features. Am J Neuroradiol. 2015 PMID: 25614472.

Wright KD, Panetta JC, Onar-Thomas A, Reddick WE, Patay Z, Qaddoumi I, Broniscer A, Robinson G, Boop FA, Klimo P Jr, Ward D, Gajjar A, Stewart CF. Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections. Cancer Chemotherapy and Pharmacology 75(1):27-35, 2015. PMID: 25342291

Patay Z, Parra C, Hawk H, George A, Li Y, Scoggins M, Broniscer A, Ogg RJ. Quantitative Longitudinal Evaluation of Diaschisis-Related Cerebellar Perfusion and Diffusion Parameters in Patients with Supratentorial Hemispheric High-Grade Gliomas After Surgery. The Cerebellum 13(5):580-587, 2014. PMID: 24917518

Patay Z, Orr BA, Shulkin BL, Hwang SN, Ying Y, Broniscer A. Successive distinct high-grade gliomas in L-2-hydroxyglutaric aciduria. Journal of inherited metabolic disease. J Inherit Metab Dis 38(2):273-7, 2014. PMDI: 25338511.

Conway AE, Reddick WE, Li Y, Yuan Y, Glass JO, Baker JN, Kun LE, Broniscer A, Patay Z. “Occult” post-contrast signal enhancement in pediatric diffuse intrinsic pontine glioma is the MRI marker of angiogenesis? Neuroradiology 56(5):405-412, 2014. PMID: 24626721

Harreld JH, Sabin ND, Rossi MG, Awwad R, Reddick WE, Yuan Y, Glass JO, Ji Q, Gajjar A, Patay Z. Elevated cerebral blood volume contributes to increased FLAIR signal in the cerebral sulci of propofol-sedated children. Am J Neuroradiol 35(8):1574-1579, 2014. PMID: 24699094

Sabin ND, Santucci AK, Klimo P Jr., Hudson MM, Srivastava D, Zhang N, Kun LE, Krasin MJ, Pui CH, Patay Z, Reddick WE, Ogg RJ, Hillenbrand CM, Robison LL, Krull KR, Armstrong GT. Incidental Detection of Late Subsequent Intracranial Neoplasms with Magnetic Resonance Imaging Among Adult Survivors of Childhood Cancer. J Cancer Surviv 8(3):329-335, 2014. PMID: 24488818

Patay Z, Enterkin J, Harreld JH, Yuan Y, Löbel U, Rumboldt Z, Khan R, Boop F. MR Imaging Evaluation of Inferior Olivary Nuclei: Comparison of Postoperative Subjects with and without Posterior Fossa Syndrome. Am J Neuroradiol 35(4):797-802, 2014. PMID: 24184519

Jackson S, Patay Z, Howarth R, Panandiker ASP, Onar-Thomas A, Gajjar A., Broniscer A. Clinico-radiologic characteristics of long-term survivors of diffuse intrinsic pontine glioma. Journal Neurooncol 114(3):339-344, 2013. PMID: 23813229

Harreld JH, Helton KJ, Kaddoum RN, Reddick WE, Li Y, Glass JO, Sansgiri R, Ji Q, Feng T, Parish ME, Gajjar A, Patay Z. The effects of propofol on cerebral perfusion MRI in children. Neuroradiology 55(8):1049-1056, 2013. PMID: 23673874

Sabin ND, Merchant TE, Harreld JH, Patay Z, Klimo P, Qaddoumi I, Armstrong GT, Wright KD, Gray J, Indelicato DJ, Gajjar A. Imaging Changes In Very Young Children With Brain Tumors Treated With Chemotherapy And Proton Therapy. AJNR Am J Neuroradiology 34(2):446-50, 2013. PMID: 22821924

Helton KJ, Patay Z, Triplett BM. Fludarabine-induced severe necrotizing leukoencephalopathy in pediatric hematopoietic cell transplantation. Bone Marrow Transplantation 48(5):729-31, 2013. PMID: 23085831

Van Poppel K, Patay Z, Roberts D, Clarke DF, McGregor A, Perkins FF, Wheless JW.  Mesial temporal sclerosis in a cohort of children with SCN1A gene mutation.  J Child Neurol 27(7):893-897, 2012 PMID: 22532537

Wright KD, von der Embse K, BS, Dewire MD, Patay Z, Coleman J, Ellison DW, Gajjar A. Isochromosome 17q, MYC amplification, and large-cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases. Pediatr Blood Cancer 9(3):561-644, 2012. PMID: 22147345

Patay Z, Mills JC, Lobel U, Lambert A, Sablauer A, Ellison DW. Cerebral neoplasms in L-2 hydroxyglutaric aciduria: 3 new cases and meta-analysis of literature data. AJNR Am J Neuroradiol January 12, 2012.

Goldsberry G, Mitra D, MacDonald D, Patay Z. Accelerated myelination with motor system involvement in a neonate with immediate postnatal onset of seizures and hemimegalencephaly.Epilepsy Behav 22(2):391-394, 2011.

Miller NG, Reddick WE, Kocak M, Glass JO, Lobel U, Morris B, Gajjar A, Patay Z. Cerebellocerebral diaschisis and postsurgical posterior fossa syndrome in pediatric patients: REPLY. AJNR Am J Neuroradiol 31(9):E83, 2010.

Lobel U, Sedlacik J, Sabin ND, Kocak M, Broniscer A, Hillenbrand CM, Patay Z. Three-dimensional susceptibility-weighted imaging and two-dimensional T2*-weighted gradient-echo imaging of intratumoral hemorrhages in pediatric diffuse intrinsic pontine glioma. Neuroradiology 52(12):1167-1177, 2010.

Lobel U, Sedlacik J, Reddick WE, Kocak M, Ji Q, Broniscer A, Hillenbrand CM, Patay Z. Quantitative diffusion-weighted and dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging analysis of T2 hypointense lesion components in pediatric diffuse intrinsic pontine glioma. AJNR Am J Neuroradiol November 18, 2010.

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Brugnoletti F, Morris EB, Laningham FH, Patay Z, Pauley JL, Pui CH, Jeha S, Inaba H. Recurrent intrathecal methotrexate induced neurotoxicity in an adolescent with acute lymphoblastic leukemia: Serial clinical and radiologic findings. Pediatr BloodCancer 2(2):293-295, 2009.

Patay Z. MR imaging of acute disseminated encephalomyelitis and multiple sclerosis in children. A review. Ideggyógyászati SzemleClin Neurosci 62(3-4):77-89, 2009.

Faqeih E, Patay Z, Rahbeeni Z, Murtada J, Al Shail E, Hall JG. Localized acalvaria with craniosynostosis. Clin Dysmorphol 17(3):165-168, 2008.

Al-Hassan ZN, Rashed MS, Al-Dirbashi OY, Patay Z, Rahbeeni, Z, Abu-Amero KK. Hyperornithinemia-hyperammonemia-homocitrullinemia syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis. Journal of Neurological Sciences 264(1-2):187-194, 2008.

Nabeel A, Lach B, Al-Shail E, Patay Z. Congenital supratentorial meningeal arteriovenous malformation with hemangioma and massive arachnoid cell hyperplasia. Child's Nervous System 21(11):995-999, 2005.

Patay Z. Diffusion-weighted imaging in leukodystrophies. European Radiology 15:2284-2303, 2005.

Lach B, Al-Shail E, Patay Z. Spontaneous anaplasia in pilocytic astrocytoma of cerebellum. British Journal of Neurosurgery 17:250-252, 2003.

Kanaan I, Jallu A, Al-Watban J, Patay Z, Hessler R. Extra-axial cavernous haemangioma: Two case reports. Skull Base 11:287-295, 2001.

Al-Essa MA, Sakati NA, Bakheet SM, Patay Z, Dabbagh O, Chaves-Carbello E, Ozand PT. X-linked adrenoleukodystrophy. The Saudi experience. Saudi Med J Jan;21(1):61-71, 2000.

Al-Essa M, Bakheet S, Patay Z, Powe J, Ozand P. Clinical, fluorine-18 labeled 2-fluoro-2-deoxyglucose positron emission tomography (FDG PET), MRI of the brain, and biochemical observations in a patient with 4-hydroxybutyric aciduria, a progressive neurometabolic disease.Brain and Development 22:127-131, 2000.

Al-Essa M, Bakheet S, Patay Z, Powe J, Ozand P. Clinical and cerebral FDG PET scan in a patient with Krabbe disease. Pediatric Neurology 22:44-47, 2000.

Al-Ghamdi H, Sabbah R, Martin J, Patay Z. Primary T-cell lymphoma of the brain in children: A case report and literature review. Pediatric Heamatology and Oncology 17(4):341-343, 2000.

Al-Essa M, Rashed M, Bakheet S, Patay Z, Ozand P. Glutaric aciduria type II: observations in seven patients with neonatal- and late-onset disease. Journal of Perinatology 20(2):120-128, 2000.

Al-Essa M, Sakati N, Bakheet S, Patay Z, Dabbagh O, Chaves-Carballo E, Ozand P. X-linked adrenoleukodystrophy. The Saudi experience. Neurosciences 5:35-45, 2000.

Sheikh BY, Kanaan I, Al-Watban J, Enayi A, Patay Z. Aneurysmal bone cyst involving the skull base: report of three cases. Skull Base Surgery 9(2):145-8, 1999.

Al-Essa M, Bakheet S, Patay Z, Al-Shamsan I, Al-Sonbul A, Ozand P. 18 Fluoro-2-deoxyglucose (18 FDG) PET scan of the brain in propionic academia: clinical and MRI correlations. Brain and Development 21(5):312-7, 1999.

Al-Watban J, Al-Zahrani A, Patay Z, Hassounah M. Acrocallosal syndrome. International Journal of Neuroradiology 5(2):133-135, 1999.

Al-Essa M, Bakheet S, Patay Z, Powe J, Ozand. Normal fluorine-18-labelled 2-fluoro-2-deoxyglucose positron emission tomography and magnetic resonance imaging of the brain in Wolman disease. Journal of Inherited Metabolic Diseases 22:846-848, 1999.

Sheikh BY, Kanaan I, Al-Watban J, Enazi A, Patay Z. Aneurysmal bone cyst involving the skull base: Report of three cases. Skull Base Surgery 9(2):145-148, 1999.

Al-Essa M, Bakheet S, Patay Z, Nounou R, Ozand P. Cerebral fluorine-18 labeled 2-fluoro-2-deoxyglucose positron emission tomography (FDG PET), MRI, and clinical observations in a patient with infantile GM1 gangliosidosis. Brain and Development 21(8):559-562, 1999.

Bakheet S, Al-Essa M, Patay Z, Al-Watban J, Dhaunsi G, Powe J, Ozand P. Cerebral Fluorin-18 Fluorodeoxyglucose positron emission tomography findings in X-linked adrenoleukodystrophy.Clinical Nuclear Medicine 24:364-365, 1999.

Al-Essa M, Al-Shamsan I, Bakheet S, Patay Z, Ozand P. 18 Fluoro-2-deoxyglucose (18-FDG) PET scan of the brain in type IV 3-methylglutaconic aciduria: Clinical and MRI correlations. Brain and Development 21:24-29, 1999.

Anzalone N, Scomazzoni F, Strada L, Patay Z, Scotti G. Intracranial vascular malformations.European Radiology 8(5):685-90, 1998.

Al-Essa M, Bakheet S, Patay Z, Al-Watban J, Powe J, Joshi, Ozand P. 18 Fluoro-2-deoxyglucose (18-FDG) PET scan of the brain in glutaric aciduria type 1: Clinical and MRI correlations. Brain and Development 20:295-301, 1998.

Violon Ph, Patay Z, Braeckeveldt J, Pirotte B, Kentos A, Brotchi J, Balériaux D. An atypical infectious complication of anterior cervical surgery. Neuroradiology 39:278-281, 1997.

Brotchi J, Patay Z, Balériaux D. Interêt de l'exploration angio IRM pré- et post-opératoire lors de la réparation chirurgicale des sinus veineux intracrâniens. Neurochirurgie 42(suppl 1):74-84, 1996.

De Witte O, Patay Z, Perez R, Noterman J, Brotchi J. Association d'un anévrysme traumatique at d'un véritable anévrysme sur l'artere Sylvienne. Neurochirurgie 41(6):432-435, 1995.

Notermann J, Patay Z, De Witte O, Salmon I, Brotchi J. Amaurose unilatérale sur ostéome du sinus sphénoidal associé a un mucocele. A propos d'un cas. Neurochirurgie 41(6):419-423, 1995

Patay Z. The role of computed tomography (CT) in the detection of the early complications of petrous bone fractures. Clinical Neuroscience 48(11-12):388-400, 1995.

David Ph, Cosaert J, Patay Z, Leproux F, Balériaux D. Anatomie de l'encéphale en imagerie par résonance magnétique. Radiologie 14(2):55-66, 1994.

Patay Z, Tournade A, Balériaux D, Tajahmady T, Berky M. Imaging of the lumbar synovio-articular cysts. Ideggyógyászati Szemle 46(11-12):408-418, 1993.

Tournade A, Patay Z, Krupa P, Tajahmady T. A comparative study of the anatomical, radiological and therapeutic features of the lumbar facet joints. Neuroradiology 34:257-261, 1992.

Patay Z, Tournade A, Berky M. Transient tumor attack. Ideggyógyászati Szemle 45(7-8):234-244, 1992.

Tournade A, Patay Z, Tajahmady T, Braun JP. Apport de la discographie au diagnostic et au traitement de la hernie discale lombaire. Journal de Neuroradiologie 18:1-11, 1991.

Books, book chapters and CD-ROMs

Patay Z. Other significant metabolic diseases. In Naidich T, Castillo M, Cha, Raybaud C and Smirniotopoulos (eds): Imaging of the Brain and Spine Elsevier 2009 (in press).

Patay Z. Neurometabolic disorders. In: Encyclopedia of Diagnostic Imaging. Baert A, ed. Springer: Verlag, Berlin; 2007. ISBN: 978-3-540-35278-5.

Patay Z. Metabolic diseases. In Pediatric Neuroradiology (ed. Tortori-Donati P). Springer: Verlag, Berlin; 2005, pp.542-721. ISBN 3-540-41077-5.

Patay Z. Central nervous system: Metabolic diseases. In: Imaging Children, 2nd edition. Carty H, Brunelle F, Stringer D, Kao S, eds. Churchill-Livingstone: Edinburgh, Scotland; 2005, pp.1899-1956. ISBN: 0-443-07039-3.

Kastler B, Vetter D, Patay Z, Germain Ph (5ème édition). Principes de l'IRM. Manuel d'auto-apprentissage. Masson, Paris, 2003. ISBN 2-294-01411-1.

Patay Z, Robertson N, Cox J. Metabolic disorders in the neonate. In MRI of the neonatal brain (ed. M. Rutherford). WB Saunders, London, pp.315-347, 2002. ISBN 07020 25348.

Kastler B, Vetter D, Patay Z, Germain P. Principes de l'IRM. In: Manuel d'auto-apprentissage, 4ème édition. Masson, Paris; 2001. ISBN 2-294-00828-6.

Kastler B, Vetter D, Patay Z, Germain P. Principes de l'IRM. In: Manuel d'auto-apprentissage, 3ème édition. Masson, Paris; 1997. ISBN 2-294-00059-5.

Patay Z. Pediatric Neuroimaging: Metabolic Diseases. In: Recent Advances in Diagnostic Neuroradiology (Medical Radiology-Diagnostic Imaging), ed. Ph. Demaerel. Springer: Verlag, Berlin;2000, pp. 347-372. ISBN3-540-65723-1.

Patay Z, Kastler B, Anzalone N, Mascalchi M, Rodesch G, Rossignol L, Balériaux D. Applied MR-Neuroangiography: CD-ROM Tutorial, Second Edition. Lasion Europe, Antwerpen; 1999. ISBN 90-74512-55-0.

Kastler B, Vetter D, Patay Z, Germain P. Principes de l'IRM. Manuel d'auto-apprentissage, 2ème édition. Masson, Paris; 1997. ISBN 2-225-83223-4.

Patay Z, Kastler B, Anzalone N, Mascalchi M, Rodesch G, Rossignol L, Balériaux D. Applied MR-Neuroangiography: CD-ROM Tutorial Lasion Europe, Antwerpen, 1997. ISBN 90-74512-21-6.

Brotchi J, Patay Z, Balériaux D. Surgery of the Superior Sagittal Sinus and Neighbouring Veins. In: Surgery of the intracranial venous system. Hakuba A, ed. Springer: Verlag, Tokyo; 1996, pp 207-219.

Balériaux D, Brotchi J, David Ph, Froment JC, Patay Z, Rio F, Salmon I. MRI of Spinal Cord Diseases: CD-ROM Tutorial Lasion Europe, Antwerpen, 1995. ISBN 90-74512-05-4

Kastler B, Vetter D, Charneau D, Germain Ph, Patay ZPrincipes de l'IRM. Manuel d'auto-apprentissage. Masson, Paris, 1994. ISBN 2-225-84454-2.

Kastler B, Patay Z. MRI for Medical Professionals: Principles of Magnetic Resonance in Medical Imaging. Edizione del Centauro-Folia Neuroradiologica Udine-Milano-Budapest;1993. ISBN 88-85980-14-7.

PhD Thesis

Applied MR-Neuroangiography. Public Academic Session of Approval: June 3, 1996, Budapest, Hungary.

Last update: December 2015