ATN129: Comparing the Effectiveness of Two Alcohol+Adherence Interventions for HIV+ Youth

Comparing the Effectiveness of Two Alcohol+Adherence Interventions For HIV+ Youth (Healthy Choices 2; HC2)

Category:

Supportive Infectious Diseases Studies

Diseases Treated:

HIV

Eligibility Overview:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant receives services at St. Jude.
  • Participant has HIV-1 Infection.
  • Participant is between the ages of 16 years and 24 years.
  • Participant has been offered a prescription for antiretroviral (ARV) medications.
  • Participant is able to understand, read, and speak English.
  • Participant has used alcohol in the last 12 weeks prior to screening.

Description

This study is being done to learn more about healthy choices (HC) in youth living with HIV. This study will compare a type of counseling called Motivational Enhancement Therapy (MET) which will be conducted either in home (or other place in the community agreed on by you and the site staff) or in a clinic can help the participant do better with decreasing their alcohol use and other things like seeing their doctor and taking medicine. The intervention consists of four (4) sessions over a twelve (12) week period. Participants will be randomized (like “flipping a coin”) to receive either clinic-based or home based HC sessions. At each site, a community health worker (CHW) who is already a member of the HIV care team will deliver the intervention to both groups. The study also would like to find out if doing better with these things reduces the amount of HIV virus in your blood and helps you feel better.

Objectives

  • To compare the effectiveness of home-based versus clinic-based delivery of MET in real world clinical settings by on-site CHW’s
  • To compare the cost-effectiveness of home based versus clinic-based delivery of MET
  • To determine individual (mental health), interpersonal (social support), and environmental (life events) factors that moderate effectiveness
  • To pilot a sustainable model of MET use in real world adolescent HIV care settings

Eligibility criteria, among others, include:

  • Participant receives services at St. Jude.
  • Participant has HIV-1 Infection as documented in the participant’s medical record.
  • Participant is between the ages of 16 years and 0 days and 24 years and 364 days at the time of baseline data collection.
  • Participant has been offered a prescription for antiretroviral (ARV) medications.
  • Participant is able to understand, read, and speak English.
  • Participant has used alcohol in the last 12 weeks prior to screening.

Principal Investigator

Aditya Gaur, MD

St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105  USA
Voice: 1-888-226-4343 or 901-595-4055
24-Hour Emergency Access Pager: 1-800-349-4334

Referring or consulting clinicians only: protocolinfo@stjude.org
For all other inquiries about St. Jude Children's Research Hospital studies: referralinfo@stjude.org

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.