LACOUT: Lactation Outcomes among Survivors of Pediatric Cancer

Category:

Long-term Effects

Eligibility Overview:

This is a non-therapeutic clinical trial open to St. Jude patients only.

Participant is a St. Jude Life or ACT (After Completion of Therapy) patient.

Description

This study is enrolling participants who are female survivors of pediatric cancer and who have had at least one live birth. Childhood cancer treatments are known to cause late effects (after treatment) involving the endocrine system; normal lactation is dependent on cooperating factors of the endocrine system. There is concern for breastfeeding difficulties due to the possible late effects from cancer treatment in survivors of pediatric cancer and include:  failure to lactate, the inability to produce enough breast milk to feed an infant, and unplanned, unwanted weaning. This study is being undertaken because there is limited information about the burden of lactation related problems among childhood cancer survivors; knowing what factors influence successful breastfeeding will help in counseling survivors before and after pregnancy. 

Objectives

Aim I

1. To examine the association between pediatric cancer histories/specific therapies and breastfeeding outcomes. 

2. To examine associations of growth hormone deficiency, hypothyroidism, diabetes mellitus and obesity and lactation outcomes (success/failure). 

Aim II

1. Compare breastfeeding outcomes between childhood cancer survivors and healthy mothers.

Inclusion criteria

1. Participant is a St. Jude Life or ACT (After Completion of Therapy) patient.

2. Participant is eighteen (18) years of age or older and has reported a live birth after childhood cancer diagnosis and treatment (currently pregnant women are eligible if they have reported a live birth after cancer diagnosis and treatment).

Exclusion criteria

1. Participant is unable to read and write.

2. Participant is unable to read and understand English.

For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children’s Research Hospital at 1-866-2ST-JUDE (1-866-278-5833)

Contact

Susan Ogg, RN

St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105  USA
Voice: 1-888-226-4343 or 901-595-4055
24-Hour Emergency Access Pager: 1-800-349-4334
Email: referralinfo@stjude.org

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.