LITE: Light Therapy to Increase Energy in Adolescents with Solid Tumors: A Pilot Study

Categories:

Psychology

Supportive Solid Tumor Studies

Diseases Treated:

Solid tumors

Eligibility Overview:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant is between the ages of twelve (12) and eighteen (18) years old. 
  • Participant has been diagnosed with a solid tumor within the past thirty (30) days. 
  • Participant is not blind and does not have a history of eye disease including, but not limited to macular degeneration, or other diagnosed retinal problems. 
  • Participant has not initiated antidepressant medication, including either SSRIs in the past month, and MAOIs in the past two months. 
  • Participant has not undergone laser corrective eye surgery in the past thirty (30) days.

Description

This study will enroll participants who have been diagnosed with a solid tumor. The study wants to see how likely adolescents with cancer are to use light therapy as an intervention that may help improve fatigue associated with cancer treatment. Fatigue is one of the most common and upsetting symptoms reported by children and adolescents receiving cancer treatment. There is some data that suggests using light therapy can help reduce fatigue. The study team would like to see if a particular type of light therapy, Bright White Light (BWL) or Dim Red Light (DRL) is more effective than the other. In this study BWL and DRL will be compared to each other to determine their effect in reducing fatigue in cancer patients.

Primary Objectives

  • To estimate the feasibility and acceptability of a BWL intervention compared to a DRL standard comparison group in adolescent solid tumor patients. 
  • To estimate the rates of consent to a BWL intervention compared to DRL in adolescent solid tumor patients. 
  • To estimate the rates of adherence to the intervention in adolescent solid tumor patients for each the intervention and comparison groups. 
  • To estimate the rates of side effects in a BWL intervention trial. 

Eligibility Criteria (among others)

  • Participant is between the ages of twelve (12) and eighteen (18) years old. 
  • Participant has been diagnosed with a solid tumor within the past thirty (30) days. 
  • Participant is not blind and does not have a history of eye disease including, but not limited to macular degeneration, or other diagnosed retinal problems. 
  • Participant has not initiated antidepressant medication, including either SSRIs in the past month, and MAOIs in the past two months. 
  • Participant has not undergone laser corrective eye surgery in the past thirty (30) days. 

For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children’s Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).

Principal Investigator

Valerie Crabtree, PhD

St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105  USA
Voice: 1-888-226-4343 or 901-595-4055
24-Hour Emergency Access Pager: 1-800-349-4334

Referring or consulting clinicians only: protocolinfo@stjude.org
For all other inquiries about St. Jude Children's Research Hospital studies: referralinfo@stjude.org

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.