This is a non-therapeutic clinical trial that is only open to St. Jude patients.
- Participant has a diagnosis of osteonecrosis and a hematologic malignancy or sickle cell disease.
- Participant is a candidate for hip core decompression surgery.
- Participant is 8 to 29 years of age.
Osteonecrosis is a disease caused by reduced blood flow to bones in the joints. This study will enroll participants who will be having hip core decompression surgery to treat osteonecrosis. In people with healthy bones, new bone is always replacing old bone. However, in people with osteonecrosis the lack of blood causes the bone to break down faster than the body can make enough new bone. The bone starts to die and breakdown. The aim of this study is to describe functional outcomes among participants that have received hip core decompression for osteonecrosis of the hip.
To describe functional outcomes of children, adolescents, and young adults with osteonecrosis of the femoral head following hip core decompression surgery. Parameters assessed will include pain, functional mobility, endurance, quality of life, and gait patterns pre-operatively and post-operatively over time.
- Participant has a diagnosis of osteonecrosis.
- Participant has a diagnosis of a hematologic malignancy, or sickle cell disease.
- Participant is considered an acceptable candidate for hip core decompression surgery by physician and/or orthopedic surgeon.
- Participant is greater than or equal to eight (8) and less than or equal to twenty-nine years of age.
- Participant does not have a serious, non-healing wound, ulcer or bone fracture.
- Participant has not had an amputation or reconstructive surgery of the lower extremities.
- Participant does not have a pre-morbid condition that prevents participant from ambulating.
Brian DeFeo, DPT
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105 USA
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The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.