ONFUNC: Functional Outcomes For Children, Adolescents, and Young Adults With Osteonecrosis Following Hip Core Decompression

Category:

Long-term Effects

Eligibility Overview:

This is a non-therapeutic clinical trial that is only open to St. Jude patients.

  • Participant has a diagnosis of osteonecrosis and a hematologic malignancy or sickle cell disease.
  • Participant is a candidate for hip core decompression surgery.
  • Participant is 8 to 29 years of age.

Description

Osteonecrosis is a disease caused by reduced blood flow to bones in the joints. This study will enroll participants who will be having hip core decompression surgery to treat osteonecrosis. In people with healthy bones, new bone is always replacing old bone. However, in people with osteonecrosis the lack of blood causes the bone to break down faster than the body can make enough new bone. The bone starts to die and breakdown. The aim of this study is to describe functional outcomes among participants that have received hip core decompression for osteonecrosis of the hip.

Primary Objective

To describe functional outcomes of children, adolescents, and young adults with osteonecrosis of the femoral head following hip core decompression surgery. Parameters assessed will include pain, functional mobility, endurance, quality of life, and gait patterns pre-operatively and post-operatively over time.

Eligibility Criteria

  • Participant has a diagnosis of osteonecrosis.
  • Participant has a diagnosis of a hematologic malignancy, or sickle cell disease.
  • Participant is considered an acceptable candidate for hip core decompression surgery by physician and/or orthopedic surgeon.
  • Participant is greater than or equal to eight (8) and less than or equal to twenty-nine years of age.
  • Participant does not have a serious, non-healing wound, ulcer or bone fracture.
  • Participant has not had an amputation or reconstructive surgery of the lower extremities.
  • Participant does not have a pre-morbid condition that prevents participant from ambulating.

Contact

Brian DeFeo, DPT

St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105  USA
Voice: 1-888-226-4343 or 901-595-4055
24-Hour Emergency Access Pager: 1-800-349-4334

Referring or consulting clinicians only: protocolinfo@stjude.org
For all other inquiries about St. Jude Children's Research Hospital studies: referralinfo@stjude.org

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