Non-therapeutic protocols address such issues as side effects or long-term effects of therapy, quality of life, making testing easier on the children, prevention of pain, and issues related to nutrition and stress. There are also tissue and blood banking protocols for laboratory researchers who are studying diseases and searching for underlying causes and cures. The research at St. Jude is designed to include all aspects related to the care of sick children and their families.
St. Jude Clinical Trials
APNEA: Sleep Apnea in Hodgkin Lymphoma Survivors Treated with Radiation to the Chest
Diseases Treated:
Eligibility:
Hodgkin lymphoma survivor
- Patient eligible for the St. Jude LIFE study
- Treated with thoracic radiation for Hodgkin lymphoma
- At least 18 years old
- At least 5 years from original diagnosis
- If participating remotely, must have Wi-Fi access
Comparison group
- Non-patient volunteer (Cannot be sibling, parent or child of the survivor participant)
- At least 18 years old
- Lives in the U.S.
- If participating remotely, must have Wi-Fi access
DSCOG: Learning, Behavior and Social Skills in Survivors of Childhood Leukemia with Down syndrome
Diseases Treated:
Eligibility:
This is a non-therapeutic clinical trial that is open only to patients who were treated at St. Jude Children’s Research Hospital since 1980 and are currently followed at the hospital.
- St. Jude Children’s Research Hospital patient with acute leukemia (i.e., ALL or AML)
- Trisomy 21 Down syndrome diagnosis
- Completed all cancer therapy at St. Jude since 1980 and at least six months prior to study visit
- English as the primary language
G4K: Genomes for Kids
Diseases Treated:
Non-therapeutic
Eligibility:
This is a non-therapeutic clinical trial that is open to St. Jude patients.
- Solid tumor or liquid tumor (cancerous or non-cancerous)
Collaborative Clinical Trials
ALTE1631: Web-based Exercise Study for Children and Adolescents with Cancer
Diseases Treated:
leukemia, solid tumor, brain tumor, lymphoma, carcinoma
Eligibility:
This is a non-therapeutic clinical trial open to patients receiving treatment at a Children’s Oncology Group (COG)-affiliated institution.
- At least 8 years old and younger than 16 years old
- Diagnosed with childhood cancer, in remission
- Completed therapy within the past 12 months
- Performance status corresponding to ECOG scores of 0, 1, 2
- Fewer than 420 minutes of moderate to vigorous physical activity (MVPA) over the last week
- Able to write and read English, Spanish or French (patient and at least one parent/guardian)
- Not pregnant
NCBP01: Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation
Diseases Treated:
Leukemia and other blood diseases
Eligibility:
This is a non-therapeutic clinical trial that is only open to St. Jude patients.
- Participant is receiving an allogeneic hematopoietic stem cell (HSC) transplant at St. Jude Children's Research Hospital using an unlicensed cord blood unit (CBU).
- Participant may be of any age and either gender.
- Participant has a medical disorder affecting the hematopoietic system that is inherited, acquired, or a result from myeloablative treatment.
- Participant is receiving HPC-CORD BLOOD product manufactured by NCBP (at least one, if the graft contains more than one units).