Martine Roussel, PhD

Department of Tumor Cell Biology

Chair: Charles J. Sherr, MD, PhD

Departmental Focus

Members of this department attempt to understand how oncogenes, tumor suppressors and checkpoint monitors of cellular stress govern tumor initiation, progression, and responses to cancer therapy. Identifying key regulatory proteins, defining their mechanisms of action, and determining how they function within complex signaling networks continues to provide a better understanding of the fundamental processes controlling cell proliferation, apoptosis, cell migration, and metastasis. Emphasis is placed on mouse models of particular pediatric cancers, including medulloblastoma, neuroblastoma, and acute lymphoblastic leukemia. All faculty members participate in interdepartmental Program Project Grants and basic science programs of the St. Jude Children’s Research Hospital Comprehensive Cancer Center.

Contact Us

Department of Tumor Cell Biology
MS 350, Room D5006
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678

Email: charles.sherr@stjude.org
Telephone: (901) 595-3505
Fax: (901) 595-2381

Preferred contact method: email

Faculty