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^{St. Jude Research}

Breakthroughs require heart

Michelle Stoltz had a choice about where to use her talents. But only one place helped her sister survive childhood cancer. This is why she came to St. Jude.

Read Her Story

Zhexin Zhu, PhD Postdoctoral Research Associate

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Kendall Wills Researcher

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Sandi Radko-Juettner Graduate Student

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Janet Partridge, PhD Principal Scientist

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Jackie Myers, PhD Lead Bioinformatics Analyst

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Priya Mittal, PhD Postdoctoral Research Associate

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Hayden Malone Graduate Student

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Yiannis Drosos, PhD Senior Scientist

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Jordan Cockfield, PhD Postdoctoral Research Associate

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Raymond Carter Researcher

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NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.

Drosos Y et al, Mol Cell. 2022 Jul 7;82(13):2472-2489.e8.

A first-generation pediatric cancer dependency map

Dharia NV et al. Nature Genetics, 2021

Small-molecule and CRISPR screening converge to reveal receptor tyrosine kinase dependencies in pediatric rhabdoid tumors

Oberlick EM et al. Cell Rep, 2019

Partitioning of chemotherapeutics into nuclear condensates - opening the door to new approaches for drug development

Howard TP et al. Mol Cell, 2020

BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors

Wang X et al. Nat Commun, 2019

The SWI/SNF complex in cancer – biology, biomarkers, and therapy

Mittal P et al. Nat Rev Clin Oncol, 2020

Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation

Erkek S et al. Cancer Cell, 2019

Rhabdoid tumors are sensitive to the protein-translation inhibitor homoharringtonine.

Howard TP et al. Clin Cancer Res, 2020

MDM2 and MDM4 are therapeutic vulnerabilities in malignant rhabdoid tumors

Howard TP et al. Cancer Res, 2019

Lab Alumni

Erich Damm, PhD

Role: Postdoctoral Fellow
Tenure: 2014-2019
Post-lab experience: Assistant Professor, Biology, Virginia Commonwealth University
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Jamie Genthe, PhD

Role: Postdoctoral Fellow
Tenure: 2014-2019
Post-lab experience: Senior Manager, Early Clinical Development, Cerus Corp.
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Nikki Glenn, PhD

Role: Postdoctoral Fellow
Tenure: 2014-2019
Post-lab experience: Assistant Professor, Biology, Belmont University
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D. Spencer Mangum, MD

Role: Clinical Fellow
Tenure: 2015-2019
Post-lab experience: Attending Physician, Pediatric Hematology/Oncology, Nemours Center for Cancer and Blood Disorders

Satish Nandakumar, PhD

Role: Graduate Student / Postdoc
Tenure: 2014
Post-lab experience: Assistant Professor, Cell Biology, Albert Einstein College of Medicine
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Sarah Rothschild, PhD

Role: Postdoctoral Fellow
Tenure: 2013-2015
Post-lab experience: Assistant Professor, Center for Integrative Life Sciences, Virginia Commonwealth University

Sarah Shore

Role: Undergraduate researcher
Tenure: 2013-2015
Post-lab experience: MD Candidate, University of Tennessee Health Sciences Center
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Robyn Umans, PhD

Role: Graduate Student
Tenure: 2014-2015
Post-lab experience: Scientist, Atsena Therapeutics
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