About the lab

A native of Manchester, England, Dr. Lee earned his PhD from the University of Newcastle-upon-Tyne and subsequently held postdoctoral research fellowship positions at Colorado State University and the University of Oxford. After appointments at the National Institutes of Health and the University of Tennessee Health Science Center, College of Pharmacy, he joined the Department of Chemical Biology & Therapeutics at St. Jude in 2009, and holds the Endowed Chair in Medicinal Chemistry. Dr. Lee’s research focuses on medicinal chemistry and structure-based drug design, with an emphasis on inhibitors to treat drug-resistant bacterial infections. His research program’s impact can be seen in nearly a dozen patents, more than 160 peer-review publications, and the advancement of two of his drug candidates into clinical trials. Dr. Lee is the co-director of the St. Jude NIH-supported T32 Infectious Disease Therapeutics Postdoctoral Training Program. 

Science Team

Meet the team

Jose Alejo, PhD
  • Jose Alejo, PhD
  • Scientist
Roger B. Altman
  • Roger B. Altman
  • Director of Lab Operations
Sukanta Bar, PhD
  • Sukanta Bar, PhD
  • Scientist
Kanokporn Chattrakun, PhD
  • Kanokporn Chattrakun, PhD
  • Postdoctoral Research Associate
 Francisco (Aaron) Cruz Navarrete, PhD
  • Francisco (Aaron) Cruz Navarrete, PhD
  • Postdoctoral Research Associate
Efren Garcia-Maldonado, PhD
  • Efren Garcia-Maldonado, PhD
  • Sr. Researcher
Zeliha Kilic
  • Zeliha Kilic
  • Staff Scientific Computing Engineer
Roman Kiselev, PhD
  • Roman Kiselev, PhD
  • Scientific Computing Engineer
Max Martin, PhD
  • Max Martin, PhD
  • Postdoctoral Research Associate
Nitish Mishra, PhD
  • Nitish Mishra, PhD
  • Senior Computational Research Scientist
Arnab Modak, PhD
  • Arnab Modak, PhD
  • Scientist
Kundhavai Natchiar, PhD
  • Kundhavai Natchiar, PhD
  • Scientist
Rakesh Paul
  • Rakesh Paul
  • Scientist
Anand Singh, PhD
  • Anand Singh, PhD
  • Scientist
Daniel S. Terry, PhD
  • Daniel S. Terry, PhD
  • Senior Scientist
Zoe Watson, PhD
  • Zoe Watson, PhD
  • Postdoctoral Research Associate

Lab Alumni

Li Cheng, PhD

  • Role: Postdoctoral Research Associate
  • Tenure: January 2018-July 2020
  • Post-lab experience: Deputy Director of Production Development and Preclinical Study Dept, GenAssist Therapeutics, China

Erich Damm, PhD

  • Role: Postdoctoral Fellow
  • Tenure: 2014-2019
  • Post-lab experience: Assistant Professor, Biology, Virginia Commonwealth University
  • LinkedIn

Jamie Genthe, PhD

  • Role: Postdoctoral Fellow
  • Tenure: 2014-2019
  • Post-lab experience: Senior Manager, Early Clinical Development, Cerus Corp.
  • LinkedIn

Nikki Glenn, PhD

  • Role: Postdoctoral Fellow
  • Tenure: 2014-2019
  • Post-lab experience: Assistant Professor, Biology, Belmont University
  • LinkedIn

Yanghua He

  • Role: Postdoctoral Research Associate
  • Tenure: Jun 2017 - Jun 2019
  • Post-lab experience: Assistant professor, University of Hawaii at Manoa.

D. Spencer Mangum, MD

  • Role: Clinical Fellow
  • Tenure: 2015-2019
  • Post-lab experience: Attending Physician, Pediatric Hematology/Oncology, Nemours Center for Cancer and Blood Disorders

Satish Nandakumar, PhD

  • Role: Graduate Student / Postdoc
  • Tenure: 2014
  • Post-lab experience: Assistant Professor, Cell Biology, Albert Einstein College of Medicine
  • LinkedIn

Sarah Rothschild, PhD

  • Role: Postdoctoral Fellow
  • Tenure: 2013-2015
  • Post-lab experience: Assistant Professor, Center for Integrative Life Sciences, Virginia Commonwealth University

Sarah Shore

  • Role: Undergraduate researcher
  • Tenure: 2013-2015
  • Post-lab experience: MD Candidate, University of Tennessee Health Sciences Center
  • LinkedIn

Xing Tang

  • Role: Bioinformatics Research Scientist
  • Tenure: Aug 2016 - Aug 2018
  • Post-lab experience: Regor Therapeutics Group

Robyn Umans, PhD

  • Role: Graduate Student
  • Tenure: 2014-2015
  • Post-lab experience: Scientist, Atsena Therapeutics
  • LinkedIn
  • karla-chavez
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    Summary of HPV Vaccination in Tennessee, recorded 04/27/2023
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  • Universal Live Attenuated Pneumonia Vaccine (SJ-11-0001) Updated
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People may not have a good sense of where it (COVID-19) falls relative to normal life. And the truth is it’s still worse than the flu in some demographics, It’s a much more complicated virus than flu. The fundamental virology is just so much more difficult.

Paul Thomas, PhD