John A. Sandoval, MD
John A. Sandoval, MD

John A. Sandoval, MD

Assistant Member, St. Jude Faculty



MD – Texas A&M Health Science Center, College Station

Clinical interests

  • Pediatric surgical oncology

Research interests

  • Preclinical and orthotopic models of the pediatric solid malignancies
  • Identification and characterization> novel Phase I agents for the treatment of pediatric solid tumors
  • Biomarkers for the early diagnosis of advanced stage pediatric solid tumors

Selected Publications

Sandoval JA, Malkas LH, Hickey RJ. Clinical significance of serum biomarkers in pediatric solid mediastinal and abdominal tumors. Int J Mol Sci 13(1):1126-1153, 2012.

Sandoval JA. Abdominal pain. In Guide to Pediatric Urology and Surgery in Clinical Practice. Godbole P, Koyle M, Wilcox D, eds. 2010.

Kumar HR, Sandoval JA, Lovell MA, Bealer JF. Primary pancreatic neuroblastoma: An unusual tumor in infancy. J Pediatr Surg 45:642-646, 2010.

Kumar HR, Zhong X, Hickey RJ, Malkas LH, Sandoval JA. Oncoproteomics of neuroblastoma: A blueprint for future progress. Curr Proteomics 7(1); 1-14, 2010.

Sandoval JA, Karrer FM, Calkins CM. Gastrointestinal Foreign Bodies. eMedicine from WebMD. Updated March 03, 2009.

Kumar HK, Zhong XL, Sandoval JA, Hickey RJ, Malkas LH. The Applications of Emerging Molecular Technologies in Glioblastoma Multiforme. Expert Rev Neurother 8(10):1497-1506, 2008.

Zyromski NJ, Sandoval JA, Pitt HA, Ladd AP, Fogel EL, Mattar WE, Sandrasegaran K, Amrheim DW, Lillemoe KD, Grosfeld JL. Annular Pancreas: Differences in Children and Adults. J Am Coll Surg 206(5):1019-25, 2008.

Sandoval JA, Sheehan MP, Stonerock CE, Shafique S, Rescorla FJ, Dalsing MC. Incidence, risk factors, and treatment patterns for deep venous thrombosis in hospitalized children: an increasing population at risk. J Vasc Surg 47(4):837-43, 2008.

Novotny N, Grosfeld JL, Turner KE, Rescorla FJ, Hickey RJ, Malkas LH, Sandoval JA. Oxidative status in neuroblastoma: A source of stress? J Pediatr Surg 43(2):330-4, 2008.

Sandoval JA, Turner KE, Hoelz DJ, Rescorla FJ, Hickey RJ, Malkas LH. Serum Protein Profiling to Identify High-Risk Neuroblastoma: Preclinical Relevance of Blood-Based Biomarkers. J Surg Res 142(2):268-74, 2007.

Sandoval JA, Eppstein AC, Hoelz DJ, Klein PJ, Linebarger JH, Turner KE, Rescorla FJ, Hickey RJ, Malkas LH, Schmidt CM. Proteomic Analysis of Neuroblastoma Subtypes in Response to MAPK Inhibition: Profiling Multiple Targets of Cancer Kinase Signaling. J Surg Res 134(1):61-7, 2006.

Sandoval JA, Dobrolecki LE, Huang S, Grosfeld JL, Hickey RJ, Malkas LH. Neuroblastoma detection using serum proteomic profiling: A novel mining technique for cancer? J Pediatr Surg 41(4):639-46, 2006.

Eppstein AC, Sandoval JA, Klein PJ, Woodruff HA, Grosfeld JL, Hickey RJ, Malkas LH, Schmidt CM. Differential Signaling Response of Neuroblastoma to MEK Activity Inhibitor Predicts Resistance to MAP Kinase Based Treatment Strategies. J Pediatr Surg 41(1):245-51, 2006.

Sandoval JA, Hoelz DJ, Woodruff HA, Powell RL, Jay CL, Grosfeld JL, Hickey RJ, Malkas LH. Novel peptides secreted from human neuroblastoma: Useful clinical tools? J Pediatr Surg 41(1):252-9, 2006.

Sandoval JA, Grosfeld JL, Hickey RJ, Malkas LH. Structural Analysis of the Human Neuroblastoma DNA Replication Complex: Insights into Faulty Proliferation. J Pediatr Surg 41(1):266-70, 2006.

Sandoval JA, Lou D, Bouchard CM, Davis MM, Engum SA, Grosfeld JL. The Hole Truth: Comparative Analysis of 4-ply vs. 8-ply Small Intestinal Submucosa (SIS) Diaphragmatic Hernia Repair in a Growing Animal Model. J Pediatr Surg 41(3):518-23, 2006.

Escobar MA, Hoelz DJ, Sandoval JA, Grosfeld JL, Hickey RJ, Malkas LH. Profiling of nuclear extract proteins from human neuroblastoma cell lines: The search for fingerprints. J Pediatr Surg 40(2):349-58, 2005.

Sandoval JA, Hickey RJ, Malkas LH. Isolation and characterization of a DNA synthesome from a neuroblastoma cell line. J Pediatr Surg 40(7):1070-1077, 2005.

Sandoval JA, Ladd AP, Rescorla FJ. Chapter 38 Pediatric Surgery. In Surgery Review Illustrated. Micon L, Azuaje R, Tevar A, eds. McGraw-Hill: New York, NY; 2005.

Sandoval JA. Senior Biochemistry Thesis. Isolation, Fatty Acid Composition, and Biosynthesis of N-Acylphosphatidylethanolamine in cottonseeds during imbibition. May 1996, University of North Texas. Major Professor: Dr. Kent D. Chapman.

Sandoval JA, Huang ZH, Garrett DC, Chapman KD. N-Acylphosphatidylethanolamine in dry and imbibing cottonseeds: Amounts, molecular species, and enzymatic synthesis. Plant Physiology 109:269-275, 1995.

Last update: February 2012