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American Association for the Advancement of Science (AAAS) awards the distinction to noted researcher Guillermo Oliver, Ph.D., for his work in developmental biology
St. Jude Children’s Research Hospital scientists show that a gene essential for normal development of the lymphatic system also plays a critical role in forming the valves that help maintain the body’s normal fluid balance.
Results help build a foundation for the next generation of therapies using cell-replacement strategies to restore vision lost to the retinal degeneration associated with glaucoma, diabetic retinopathy and age-related macular degeneration.
St. Jude Children’s Research Hospital scientists identify a novel feedback mechanism that regulates differentiation of adult neural stem cells.
St. Jude scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most common developmental malformation of the anterior brain and face in newborns, but also help in understanding the intricate process by which the brain forms in the developing fetus.
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature—the network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new therapies for lymphatic system disorders, the researchers said.
Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.
Researchers have discovered a critical, early step in the growing vertebrate embryo that is required for the proper development of a major part of what is often called the most complex structure in the universe-the human brain.