Structural Biology

Department of Structural Biology

Chair

Stephen White, DPhil


Departmental Focus

A full understanding of how a biological macromolecule functions is not possible until its three-dimensional structure has been determined at the molecular level. Structural information is also essential for designing drugs that can mediate function and treat disease. These studies are typically performed by using X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computer graphics. The Department of Structural Biology brings this expertise and these techniques to St. Jude.


Contact Us

Department of Structural Biology
MS 311, Room D1024
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678

Email: stephen.white@stjude.org
Phone: (901) 595-3040
FAX: (901) 595-3032

Preferred contact method: email


Faculty

Don Bashford, PhD  Computational molecular biophysics

Eric J. Enemark, PhD  Molecular mechanisms of DNA replication

Richard Kriwacki, PhD  Structural basis of tumor suppressor function

Tanja Mittag, PhD  Dynamic protein complexes in signal transduction

Tudor Moldoveanu, PhD  Programmed cell death in health and disease

Junmin Peng, PhD  Proteomics to ubiquitin biology and human disease

Brenda Schulman, PhD  Cellular regulation by ubiquitin-like proteins

Stephen White, DPhil  Structural analyses of catalysis and DNA repair

Jie Zheng, PhD  Protein NMR and structure-based drug discovery