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    Brindle: News Releases & Feature Stories

     
    07/18/2007
    "Plumber" protein uses different tools to turn on genes

    St. Jude investigators have discovered how a single molecular "on switch" triggers gene activity that might cause effects ranging from learning and memory capabilities to glucose production in the liver.

     
     
    01/03/2006
    Genetic secrets hold promise for treating solid tumors

    A biochemical mechanism that cells use to cope with hypoxia (lack of oxygen) actually cooperates with a less well-known mechanism that helps increase the expression of those hypoxia-sensitive genes.

     
     
    12/06/2005
    Finding suggests new diabetes treatment

    Novel compounds that prevent a protein called TORC2 from moving from the cytoplasm and into the nuclei of liver cells might be able to reduce high blood sugar in people with diabetes.

     
     
    02/24/2004
    St. Jude study finds direct link between CBP gene and lymphoma

    Inactivation of the gene CBP in certain immature white blood cells of mice causes lymphoma, a type of cancer also found in humans. The cancer is accompanied by changes in the expression of specific genes associated with development of the disease.