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Associated Infectious Diseases Studies : Human Immunodeficiency Virus (HIV)
High levels of LDL cholesterol can increase the risk of developing cardiovascular disease. Protease inhibitors (a type of medicine that decreases the level of HIV virus in the blood) have been found to increase LDL cholesterol in some people. Sometimes, changes in diet and exercise can lower levels of LDL cholesterol in people’s blood. Lipitor (generic atorvastatin) is a type of medicine used to lower cholesterol in people who have tried exercising and changing their diet, but whose cholesterol levels remain high.
Lipitor is FDA approved in adults, and in uninfected children in doses of 10mg and 20mg. It has not been studied in HIV-infected children who are taking a protease inhibitor which can increase the level of Lipitor in your blood.
Aditya Gaur, MD
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.