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Genetic counseling and testing proposed for patients with the brain tumor medulloblastoma
05/09/2018
Researchers created the first genetic screening guidelines for medulloblastoma patients after identifying gene variations that make carriers susceptible.
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Discovery of likely subtypes of rare childhood brain tumor signals diagnostic advance
02/25/2016
Molecular classification of rare brain tumors CNS-PNET likely to improve diagnosis and set stage for targeted therapies.
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Study finds significant cognitive impairment in adult survivors of childhood brain tumors
02/01/2016
St. Jude LIFE study reports that decades after treatment, adult survivors of childhood brain tumors often face significant cognitive challenges.
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Researchers mine the epigenome to identify likely origins of childhood brain tumor subtype
01/27/2016
Epigenome yields insights into medulloblastoma, the most common malignant pediatric brain tumor, including likely cell of origin for Group 4 subtype.
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Targeted therapy shows effectiveness against a subtype of the brain tumor medulloblastoma
07/29/2015
A subset of medulloblastoma tumors briefly stopped growing or disappeared during treatment with the targeted drug vismodegib.
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Eighteen genes identified that contribute to childhood brain tumor ependymoma
06/18/2015
St. Jude discovery lays the foundation for developing new chemotherapy agents and finds evidence that statins slow growth of ependymoma tumor cells.
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First cancer-promoting oncogenes discovered in rare brain tumor of children and adults
05/11/2015
Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer.
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Gene sequencing project discovers mutations tied to deadly brain tumors in young children
04/06/2014
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients.
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Gene sequencing project discovers common driver of a childhood brain tumor
02/19/2014
St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers.
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Gene sequencing project finds new mutations to blame for a majority of brain tumor subtype
04/14/2013
The St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project advances understanding of genetic defects underlying childhood low-grade gliomas and identifies promising new drug therapies.
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Gene sequencing project identifies potential drug targets in common childhood brain tumor
06/20/2012
St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project lifts lid on the most aggressive subtype of medulloblastoma and finds genes that cooperate in tumor development.
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Cancer sequencing initiative discovers mutations tied to aggressive childhood brain tumors
01/29/2012
St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project provides first evidence linking cancer to mutations in genes involved in DNA organization. (Dr. Suzanne Baker)